SPOCK1
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Official Full Name
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -
Overview
This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The proteins function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition. -
Synonyms
SPOCK1;sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1;sparc/osteonectin, cwcv and kazal like domains proteoglycan (testican) , SPOCK, TIC1;testican-1;testican 1;Sparc/osteonectin, cwcv and kazal like domains proteoglycan 1;SPOCK;TIC1;TICN1;TESTICAN
Recombinant Proteins
- Rhesus macaque
- Human
- Mammalian Cell
- Insect Cell
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SPOCK1-4440R | Recombinant Rhesus monkey SPOCK1 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| SPOCK1-545H | Recombinant Human SPOCK1, His tagged | Insect Cell | Human | His | 1-439 a.a. |
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| SPOCK1-546H | Recombinant Human SPOCK1 protein, His-tagged | HEK293 | Human | His | 418 |
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| SPOCK1-001HCL | Recombinant Human SPOCK1 cell lysate | Insect Cell | Human | Non | 21-429 a.a. |
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| SPOCK1-4256R | Recombinant Rhesus Macaque SPOCK1 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| SPOCK1-4256R-B | Recombinant Rhesus Macaque SPOCK1 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| SPOCK1-836H | Recombinant Human SPOCK1 Protein | HEK293 | Human | 439 |
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Involved Pathway
SPOCK1 involved in several pathways and played different roles in them. We selected most pathways SPOCK1 participated on our site, such as Adipogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SPOCK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adipogenesis | E2F4,NDN,GATA2,AGT,EPAS1B,MEF2B,BSCL2,CREB1,NCOA2,BMP3 |
Protein Function
SPOCK1 has several biochemical functions, for example, calcium ion binding,cysteine-type endopeptidase inhibitor activity,metalloendopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SPOCK1 itself. We selected most functions SPOCK1 had, and list some proteins which have the same functions with SPOCK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cysteine-type endopeptidase inhibitor activity | AHSG,SERPINB4,HRG,WFDC2,SERPINB13,CSTA,SERPINB3,BIRC5A,NAIP1,CST6 |
| serine-type endopeptidase inhibitor activity | RECK,TFPIA,OVAL,SPINK11,PAPLNB,Serpina1b,SERPINB1L4,Serpina1c,COL7A1,SERPINI2 |
| calcium ion binding | CALML5,ACTN3A,CAPN1A,APCS,PCDH2AA1,TESC,ANXA3A,LDLR,CMLC1,JAG2 |
| metalloendopeptidase inhibitor activity | COL4A3,TIMP1,TIMP4,TIMP3,TIMP2,BST2,LXN,WFIKKN2,TIMP2B,SPOCK3 |
Interacting Protein
SPOCK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPOCK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SPOCK1.
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References
- Leja, J; Essaghir, A; et al. Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas. MODERN PATHOLOGY 22:261-272(2009).
