Spna2

  • Official Full Name

    spectrin alpha 2
  • Synonyms

    SPNA2;spectrin alpha 2;ENSMUSG00000057738;Spna-2;Sptan1;2610027H02Rik;2 B;2 18.0 cM;spectrin alpha chain, brain;spectrin alpha chain, brain;alpha-fodrin;alpha-II spectrin;fodrin alpha chain;alpha-spectrin 2, brain;spectrin, non-erythroid alpha chain
Cat.# Product name Source (Host) Species Tag Protein Length Price
SPNA2-5689Z Recombinant Zebrafish SPNA2 Mammalian Cells Zebrafish His

    Involved Pathway

    Spna2 involved in several pathways and played different roles in them. We selected most pathways Spna2 participated on our site, such as ARMS-mediated activation,Apoptosis,Apoptotic cleavage of cellular proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with Spna2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine Signaling in Immune system EIF4E3,TNFSF13B,BST2,FGF10B,RASGRP4,SPRED3,FGF20A,GHRB,IL17RD,TAB1
    Apoptosis HRK,PIK3CD,HMGB2,PRKACBA,LMNB1,PLEC,CASP8,PPP3R2,GAS2,CASP3B
    Apoptotic execution phase CTNNB1,CLSPN,PKP1,DSG2,DBNLB,DNM1L,GAS2,CTNNB2,DSG3,PLECA
    ARMS-mediated activation DUSP6,SPTBN2,NRG3,SPTB,SPRED1,PSMD10,NEFLB,RASGRP1,PSMD14,PSME3
    Caspase-mediated cleavage of cytoskeletal proteins CASP6L1,CASP6L2,PLECA,DBNL,DBNLA,VIML,DBNLB,GAS2,PLEC,ADD1
    Axon guidance EPHA4,JAK3,EPHB4,NTN1B,CXCL12,PHB,FRS3,ABLIM3,CAP2,MYL12A
    DAP12 interactions DUSP4,GRAP2A,NRG2A,THEM4,WDR83,FRS2,SPTBN2,DAB2IPB,CD300LB,DUSP2
    Apoptotic cleavage of cellular proteins PLEC,CASP6L1,BMX,STK24,DSG2,SATB1,CASP8L1,DSG1,DBNLA,CLSPN

    Protein Function

    Spna2 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Spna2 itself. We selected most functions Spna2 had, and list some proteins which have the same functions with Spna2. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding ANXA5B,ESYT2,EPS15L1,RPH3AL,Shh,CASQ1A,PCLO,CDH2,OIT3,CDHR3

    Interacting Protein

    Spna2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Spna2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Spna2.

    piwil2

    Resources

    References

    • Chin, MS; Hooper, LC; et al. Identification of alpha-fodrin as an autoantigen in experimental coronavirus retinopathy (ECOR). JOURNAL OF NEUROIMMUNOLOGY 272:42-50(2014).
    • Valiyaveettil, M; Alamneh, YA; et al. Cytoskeletal protein alpha-II spectrin degradation in the brain of repeated blast exposed mice. BRAIN RESEARCH 1549:32-41(2014).

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