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SPIC

Official Full Name

Spi-C transcription factor (Spi-1/PU.1 related)
Synonyms

SPIC; Spi-C transcription factor (Spi-1/PU.1 related); transcription factor Spi-C; MGC40611; SPI C; SPI-C;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	SPIC-084H	Recombinant Human SPIC Protein, HIS-tagged	E.coli	HIS	Inquiry
Human	SPIC-1516HCL	Recombinant Human SPIC 293 Cell Lysate	HEK293	Non	Inquiry
Mouse	SPIC-15881M	Recombinant Mouse SPIC Protein	Mammalian Cell	His	Inquiry
Mouse	SPIC-8644M	Recombinant Mouse SPIC Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi	Inquiry
Mouse	SPIC-8644M-B	Recombinant Mouse SPIC Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	SPIC-1340Z	Recombinant Zebrafish SPIC	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

SPIC involved in several pathways and played different roles in them. We selected most pathways SPIC participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SPIC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

SPIC has several biochemical functions, for example, RNA polymerase II transcription factor activity, sequence-specific DNA binding, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SPIC itself. We selected most functions SPIC had, and list some proteins which have the same functions with SPIC. You can find most of the proteins on our site.

Function	Related Protein
RNA polymerase II transcription factor activity, sequence-specific DNA binding	SOX15;NPAS4A;FOXB1;FOXD1L;FLI1A;LMO2;TP53;TFDP1B;FLI1B
sequence-specific DNA binding	NR1H4;SNAI2;HOXA11A;MAEL;SOX17;HOXD3;FOXI3A;OTX1A;CREMB

SPIC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPIC here. Most of them are supplied by our site. Hope this information will be useful for your research of SPIC.

Research Area

Geng, SZ; Jiao, XN; et al. Virulence determinants of Salmonella Gallinarum biovar Pullorum identified by PCR signature-tagged mutagenesis and the spiC mutant as a candidate live attenuated vaccine. VETERINARY MICROBIOLOGY 168:388-394(2014).

Shotland, Y; Kramer, H; et al. The Salmonella SpiC protein targets the mammalian Hook3 protein function to alter cellular trafficking. MOLECULAR MICROBIOLOGY 49:1565-1576(2003).

Chen, HQ; Schifferli, DM; et al. Construction, characterization, and immunogenicity of an attenuated Salmonella enterica serovar typhimurium pgtE vaccine expressing fimbriae with integrated viral epitopes from the spiC promoter. INFECTION AND IMMUNITY 71:4664-4673(2003).

Yu, XJ; Ruiz-Albert, J; et al. SpiC is required for secretion of Salmonella Pathogenicity Island 2 type III secretion system proteins. CELLULAR MICROBIOLOGY 4:531-540(2002).