SOX21

  • Official Full Name

    SRY (sex determining region Y)-box 21
  • Overview

    SRY-related HMG-box (SOX) genes encode a family of DNA-binding proteins containing a 79-amino acid HMG (high mobility group) domain that shares at least 50% sequence identity with the DNA-binding HMG box of the SRY protein (MIM 480000). SOX proteins are divided into 6 subgroups based on sequence similarity within and outside of the HMG domain. For additional background information on SOX genes, see SOX1 (MIM 602148).[supplied by OMIM, Apr 2004]
  • Synonyms

    SOX21;SRY (sex determining region Y)-box 21;SOX25;transcription factor SOX-21;SOX-A;SRY-box 21

Recombinant Proteins

  • Mouse
  • Rhesus macaque
  • Human
  • Mammalian Cell
  • HEK293
  • HEK293T
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi

    Involved Pathway

    SOX21 involved in several pathways and played different roles in them. We selected most pathways SOX21 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SOX21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    SOX21 has several biochemical functions, for example, DNA binding,RNA polymerase II transcription factor activity, sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SOX21 itself. We selected most functions SOX21 had, and list some proteins which have the same functions with SOX21. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II transcription factor activity, sequence-specific DNA binding FOXG1D,TFDP2,FOXL1,SPI1A,SOX9A,FOXG1B,RUNX2A,FOXE1,FOXA,FOXM1
    transcription factor activity, sequence-specific DNA binding IKZF2,ATF7A,HMGA1B,ZNF71,MNX2A,BRD8,THRB,POU4F1,HOXB6B,NPAS1
    DNA binding RPS3,HNF1B,ZNF653,CHD4A,CERS4A,CASP8AP2,PML,GZF1,ZNF582,ZNF729

    Interacting Protein

    SOX21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOX21 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOX21.

    Resources

    Research Area

    Neural Stem Cell Markers

    References

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