SNX12
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Official Full Name
sorting nexin 12 -
Overview
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. This gene encodes a protein of unknown function. -
Synonyms
SNX12;sorting nexin 12;sorting nexin-12;2610001F05Rik;AW045757;MGC118982;MGC118983;RGD1565585;RP23-356J7.1;SDP8;SNX 12;SNX12_HUMAN;OTTHUMP00000023487;OTTHUMP00000023488
Recombinant Proteins
- Zebrafish
- Chicken
- Rhesus macaque
- Human
- Mouse
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SNX12-11345Z | Recombinant Zebrafish SNX12 | Mammalian Cell | Zebrafish | His |
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| SNX12-3177C | Recombinant Chicken SNX12 | Mammalian Cell | Chicken | His |
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| SNX12-4389R | Recombinant Rhesus monkey SNX12 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| SNX12-7395Z | Recombinant Zebrafish SNX12 | Mammalian Cell | Zebrafish | His |
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| SNX12-7396Z | Recombinant Zebrafish SNX12 | Mammalian Cell | Zebrafish | His |
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| SNX12-7397Z | Recombinant Zebrafish SNX12 | Mammalian Cell | Zebrafish | His |
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| SNX12-1601HCL | Recombinant Human SNX12 293 Cell Lysate | HEK293 | Human | Non |
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| SNX12-4205R | Recombinant Rhesus Macaque SNX12 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| SNX12-4205R-B | Recombinant Rhesus Macaque SNX12 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| SNX12-5648H | Recombinant Human SNX12 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Snx12-6022M | Recombinant Mouse Snx12 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
SNX12 involved in several pathways and played different roles in them. We selected most pathways SNX12 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNX12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | HSPA1L,EPS15,TGFB1,CHMP2B,CYTH4,GRK1B,DNAJC6,FGFR2,WIPF2B,DNM1B |
Protein Function
SNX12 has several biochemical functions, for example, enzyme binding,phosphatidylinositol binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNX12 itself. We selected most functions SNX12 had, and list some proteins which have the same functions with SNX12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| enzyme binding | ARPC4,ARRB2,LDB2,PPP3CB,TP53,PARK7,HIST1H2AM,ZFP346,PRMT1,TOP2A |
| protein binding | BTK,CYTH2,GPR77,RMND1,NOTCH2NL,SPANXC,MAP3K7IP3,ITGAX,PPP2R3C,PHF7 |
| phosphatidylinositol binding | SNX10B,SLC12A9,HIP1RB,SEPT12,CCDC88A,SNX27B,SNX9,NOXO1,SNX9A,SNX31 |
Interacting Protein
SNX12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNX12 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNX12.
ARL6IP1;ABL1;FYN;NCK1;GRB2;pi3p;CDC5L
Resources
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References
- Wang, X; Huang, T; et al. Dysregulation of protein trafficking in neurodegeneration. MOLECULAR NEURODEGENERATION 9:-(2014).
- Angel, JM; Abel, EL; et al. Fine Mapping Reveals That Promotion Susceptibility Locus 1 (Psl1) Is a Compound Locus With Multiple Genes That Modify Susceptibility to Skin Tumor Development. G3-GENES GENOMES GENETICS 4:1071-1079(2014).
