SMC2

  • Official Full Name

    structural maintenance of chromosomes 2

  • Overview

    Structural maintenance of chromosomes 2 (SMC2) and 4 (SMC4) proteins are subunits of the condensin complex, which enables chromosome condensation and maintains the compaction of chromosomes as they separate to opposite poles during anaphase (1-3). In addi

  • Synonyms

    SMC2;structural maintenance of chromosomes 2;SMC2 (structural maintenance of chromosomes 2, yeast) like 1 , SMC2 structural maintenance of chromosomes 2 like 1 (yeast) , SMC2L1;structural maintenance of chromosomes protein 2;CAP E;hCAP E;SMC-2;SMC

Recombinant Proteins

  • Human
  • Mouse
  • Chicken
  • Zebrafish
  • E.coli
  • Mammalian Cell
  • E. coli
  • HEK293
  • Non
  • His
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
SMC2-02H Recombinant Human SMC2 Protein, Biotinylated-tagged E.coli Human Non
SMC2-15610M Recombinant Mouse SMC2 Protein Mammalian Cell Mouse His
SMC2-6783C Recombinant Chicken SMC2 Mammalian Cell Chicken His
SMC2-9947Z Recombinant Zebrafish SMC2 Mammalian Cell Zebrafish His
SMC2-055H Recombinant Human structural maintenance of chromosomes 2 Protein, His tagged E. coli Human His 476-707aa
SMC2-8469M Recombinant Mouse SMC2 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
SMC2-8469M-B Recombinant Mouse SMC2 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    SMC2 involved in several pathways and played different roles in them. We selected most pathways SMC2 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,Condensation of Prometaphase Chromosomes, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell Cycle, Mitotic TCTN2,NUPL2,ITGB3BP,DULLARD,MAPRE1A,NUMA1,DYNC1I2,CLASP1A,ESCO2,CDK5RAP2
    M Phase KIF2A,CCDC99,WAPAL,CTDNEP1A,CDCA8,NSL1,CENPH,ARPP19B,KIF18A,SETB
    Condensation of Prophase Chromosomes NCAPD3,SMC4,MCPH1,PHF8,NCAPH2,NCAPG2,SETB,SETA,H3F3D,SET
    Condensation of Prometaphase Chromosomes NCAPG,NCAPH,CSNK2B,SMC4,CSNK2A1,NCAPD2,CSNK2A2
    Mitotic Prometaphase CENPP,PDS5A,CDCA8,SGOL1,ZW10,NCAPH,RANGAP1B,ZWINT,PMF1,CENPN
    Mitotic Prophase TMEM188,CTDNEP1,SMC4,DULLARD,PHF8,SET,CTDNEP1A,NCAPG2,NEK6,MCPH1
    Cell cycle UIMC1,CCND3,HDAC5,DPF1,CCP110,CDH1-A,ORC6L,CDKN1BB,CSNK2A1,CCND1

    Protein Function

    SMC2 has several biochemical functions, for example, ATP binding,nucleotide binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMC2 itself. We selected most functions SMC2 had, and list some proteins which have the same functions with SMC2. You can find most of the proteins on our site.

    Function Related Protein
    nucleotide binding INSRA,RBFOX1,CDC34B,RBM19,MAPK8B,TTLL2,ATP1A3A,PKZ,HNRPL,TUBA1L2
    protein binding ZNF581,HOXA3,IL23,WDR4,RPL19,DCP1B,EDC4,FAM128B,RXRG,PKM2
    ATP binding PI4KA,TARS2,BAT1,DHX32A,ATP4A,CSNK1E,CDK1,ATAD5,HSP70L,ABCB10
    protein heterodimerization activity BTBD11,ATF3,PANX1,ATF4,POLE3,MYOG,FZD9,BCL2A,ROPN1B,UBXN6

    Interacting Protein

    SMC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMC2.

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