SMC1A
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Official Full Name
structural maintenance of chromosomes 1A -
Overview
Structural maintenance of chromosomes 1 (SMC1) protein is a chromosomal protein member of the cohesin complex that enables sister chromatid cohesion and plays a role in DNA repair. ATM/NBS1-dependent phosphorylation of SMC1 occurs at Ser957 and Ser966 in -
Synonyms
SMC1A;structural maintenance of chromosomes 1A;SMC1 (structural maintenance of chromosomes 1, yeast) like 1 , SMC1 structural maintenance of chromosomes 1 like 1 (yeast) , SMC1L1;structural maintenance of chromosomes protein 1A;DXS423E;KIAA0178;SB1
Recombinant Proteins
- Human
- Mouse
- Rat
- Chicken
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Avi&Fc&His
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SMC1A-2808H | Recombinant Human SMC1A, GST-tagged | E.coli | Human | GST | 685-1034aa | |
| SMC1A-2907H | Recombinant Human SMC1A protein, His-tagged | E.coli | Human | His | 685-1034 aa | |
| SMC1A-15608M | Recombinant Mouse SMC1A Protein | Mammalian Cells | Mouse | His |
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| SMC1A-5616R | Recombinant Rat SMC1A Protein | Mammalian Cells | Rat | His |
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| SMC1A-6085C | Recombinant Chicken SMC1A | Mammalian Cells | Chicken | His |
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| SMC1A-7517Z | Recombinant Zebrafish SMC1A | Mammalian Cells | Zebrafish | His |
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| SMC1A-1666HCL | Recombinant Human SMC1A 293 Cell Lysate | HEK293 | Human | Non |
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| SMC1A-5275R | Recombinant Rat SMC1A Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| SMC1A-5275R-B | Recombinant Rat SMC1A Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| SMC1A-8468M | Recombinant Mouse SMC1A Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| SMC1A-8468M-B | Recombinant Mouse SMC1A Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SMC1A involved in several pathways and played different roles in them. We selected most pathways SMC1A participated on our site, such as Cell cycle,Oocyte meiosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMC1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Oocyte meiosis | BUB1,SGOL1,YWHABA,SLK,ADCY1A,CAMK2A,PLCZ1,YWHAQB,ITPR3,MAD2L2 |
| Cell cycle | BUB3,H3F3D,MDM2,E2F3,PSMC3IP,CSNK1E,MCM6L,CTDNEP1A,HUS1,PHF8 |
Protein Function
SMC1A has several biochemical functions, for example, ATP binding,chromatin binding,mediator complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMC1A itself. We selected most functions SMC1A had, and list some proteins which have the same functions with SMC1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein heterodimerization activity | TIRAP,TXLNG,H2AFVA,SNX5,USF2,MID2,EXT1,FZD1,LIFR,HIST1H2B7 |
| ATP binding | CDKL4,RPS6KA3,HSP90AA1.2,CSNK1G2B,MAP3K2,GLUD1,MYO5C,MVK,PKZ,PDIK1L |
| microtubule motor activity | DNAH9,KIF23,KLC2,KIF3C,BBS4,KLC1A,DYNC1H1,DNHD1,KIF9,KIF3CB |
| mediator complex binding | SMC3,NIPBL,MED1 |
| poly(A) RNA binding | MAZ,EEF2,RPS21,RPL19,RBM19,FAM103A1,SRRT,HIST1H4E,PRPF3,HIST1H4H |
| chromatin binding | MB21D2,PBRM1,CHD8,MEOX1,NSBP1,RELB,DLX2,BEND6,TADA2A,RUNX2 |
| protein binding | UCN,BSCL2,S100A8,DCUN1D4,PPIB,CD300LD,SEPHS1,SKIL,FGF3,TSC2 |
Interacting Protein
SMC1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMC1A here. Most of them are supplied by our site. Hope this information will be useful for your research of SMC1A.
SMC3;RAD21;WAPAL
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