SLC4A7
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Official Full Name
solute carrier family 4, sodium bicarbonate cotransporter, member 7 -
Overview
This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012] -
Synonyms
SLC4A7;solute carrier family 4, sodium bicarbonate cotransporter, member 7;NBC2;NBC3;SBC2;NBCN1;SLC4A6;sodium bicarbonate cotransporter 3;bicarbonate transporter;solute carrier family 4 member 7;sodium bicarbonate cotransporter 2;sodium bicarbonate cotransporter 2b;electroneutral Na/HCO(3) cotransporter
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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| SLC4A7-5553R | Recombinant Rat SLC4A7 Protein | Mammalian Cells | Rat | His |
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| SLC4A7-0452H | Recombinant Human SLC4A7 Protein (E2-L1214), 8×His-MBP, Flag tagged | Insect Cells | Human | His&Flag&MBP | E2-L1214 |
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| SLC4A7-048H | Recombinant Human SLC4A7 Full Length Transmembrane protein(Nanodisc) | HEK293 | Human | Non | Full L. |
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| SLC4A7-5212R | Recombinant Rat SLC4A7 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| SLC4A7-5212R-B | Recombinant Rat SLC4A7 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
SLC4A7 involved in several pathways and played different roles in them. We selected most pathways SLC4A7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC4A7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SLC4A7 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SLC4A7 itself. We selected most functions SLC4A7 had, and list some proteins which have the same functions with SLC4A7. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
SLC4A7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC4A7 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC4A7.
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References
- Park, HJ; Rajbhandari, I; et al. Neuronal expression of sodium/bicarbonate cotransporter NBCn1 (SLC4A7) and its response to chronic metabolic acidosis. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 298:C1018-C1028(2010).
- Perry, C; Quissell, DO; et al. Electrogenic NBCe1 (SLC4A4), but not electroneutral NBCn1 (SLC4A7), cotransporter undergoes cholinergic-stimulated endocytosis in salivary ParC5 cells. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 295:C1385-C1398(2008).
