SLC47A2
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Official Full Name
solute carrier family 47, member 2 -
Overview
This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. -
Synonyms
SLC47A2;solute carrier family 47, member 2;multidrug and toxin extrusion protein 2;FLJ31196;MATE2;MATE2 K;multidrug and toxin extrusion 2;MATE-2;hMATE-2;H+/organic cation antiporter;kidney-specific H(+)/organic cation antiporter;MATE2K;MATE2-B
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC47A2-15464M | Recombinant Mouse SLC47A2 Protein | Mammalian Cells | Mouse | His |
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| SLC47A2-3875C | Recombinant Chicken SLC47A2 | Mammalian Cells | Chicken | His |
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| SLC47A2-5037Z | Recombinant Zebrafish SLC47A2 | Mammalian Cells | Zebrafish | His |
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| SLC47A2-8386M | Recombinant Mouse SLC47A2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| SLC47A2-8386M-B | Recombinant Mouse SLC47A2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SLC47A2 involved in several pathways and played different roles in them. We selected most pathways SLC47A2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC47A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SLC47A2 has several biochemical functions, for example, antiporter activity,drug transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC47A2 itself. We selected most functions SLC47A2 had, and list some proteins which have the same functions with SLC47A2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| antiporter activity | SLC7A10,SLC35C2,SLC38A3,SLC35E3,SLC25A16,SLC35D2,SLC7A8,SLC7A14,SLC9A3.2,CLCN6 |
| drug transmembrane transporter activity | SLC17A3,ABCG2D,SLC18A3B,SLC18A1,SLC22A5,SLCO1B2,SLC47A1,SLC22A18,ABCG3,SLC18A3A |
Interacting Protein
SLC47A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC47A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC47A2.
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References
- Minear, MA; Li, YJ; et al. Genetic screen of African Americans with Fuchs endothelial corneal dystrophy. MOLECULAR VISION 19:2508-2516(2013).
- Rege, J; Nakamura, Y; et al. Transcriptome Profiling Reveals Differentially Expressed Transcripts Between the Human Adrenal Zona Fasciculata and Zona Reticularis. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 99:E518-E527(2014).
