SLC35D2
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Official Full Name
solute carrier family 35, member D2 -
Overview
Nucleotide sugars, which are synthesized in the cytosol or the nucleus, are high-energy donor substrates for;glycosyltransferases located in the lumen of the endoplasmic reticulum and Golgi apparatus. Translocation of;nucleotide sugars from the cytosol into the lumen compartment is mediated by specific nucleotide sugar transporters,;such as SLC35D2 (Suda et al., 2004 (PubMed 15082721)). -
Synonyms
SLC35D2;solute carrier family 35, member D2;UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter;SQV7L;UGTrel8;Fringe connection;HFRC 1;Hfrc;HFRC1;MGC117215;MGC142139;Nucleotide sugar transporter UGTrel8;Solute carrier family 35 member D2;SQV 7L;UDP N acetylglucosamine transporter;UGTrel 8;SQV7-like protein;OTTHUMP00000021719;UDP-N-acetylglucosamine transporter;homolog of Fringe connection protein 1;UDP-galactose transporter-related protein 8
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC35D2-15400M | Recombinant Mouse SLC35D2 Protein | Mammalian Cells | Mouse | His |
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| SLC35D2-667H | Recombinant Human SLC35D2 Protein, GST-tagged | Wheat Germ | Human | GST | 1-249 aa |
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| SLC35D2-6813HF | Recombinant Full Length Human SLC35D2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 249 amino acids |
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| SLC35D2-8337M | Recombinant Mouse SLC35D2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SLC35D2-8337M-B | Recombinant Mouse SLC35D2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SLC35D2 involved in several pathways and played different roles in them. We selected most pathways SLC35D2 participated on our site, such as Glycosaminoglycan metabolism,HS-GAG biosynthesis,Heparan sulfate/heparin (HS-GAG) metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC35D2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism of carbohydrates | MAPK1IP1L,HAS3,SLC5A9,DSEL,HS3ST6,GYG1A,B3GNT2,SLC25A10,SLC25A1,SLC25A12 |
| SLC-mediated transmembrane transport | SLC7A6,SLC6A19A,SLC2A15B,LCN1,SLC29A3,SLC39A14,SLC13A3,SLCO4A1,SLC35A1,SLC12A7 |
| Metabolism | CKB,Agmo,CYP2K8,NDOR1,COX5B,AMD2,CPTP,CKBA,CYP3A5,SULT1B1 |
| Keratan sulfate biosynthesis | KERA,FMODA,PRELP,B3GNT2,B3GNT2A,ST3GAL3A,OGN,B3GNT1,OMD,B3GNT3 |
| HS-GAG biosynthesis | HS3ST6,GPC1A,GPC1B,MAPK1IP1L,Gpc2,GPC5A,HS3ST4 |
| Glycosaminoglycan metabolism | HS3ST4,SLC26A1,PRELP,B3GNT1,B3GNT2,SLC35B3,LYVE1,FMODA,CSPG5B,B3GNT3 |
| Keratan sulfate/keratin metabolism | GLB1L,B3GNT2A,B3GNT3,B3GNT1,FMODA,B3GNT2,OMD,ST3GAL3A |
| Heparan sulfate/heparin (HS-GAG) metabolism | CSPG5B,Gpc2,GLB1L,B3GAT2,HS3ST4,GPC1A,GPC1B,B4GALT7,GPC5A,HPSE |
Protein Function
SLC35D2 has several biochemical functions, for example, antiporter activity,pyrimidine nucleotide-sugar transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC35D2 itself. We selected most functions SLC35D2 had, and list some proteins which have the same functions with SLC35D2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| pyrimidine nucleotide-sugar transmembrane transporter activity | SLC35D1A,SLC35D1B |
| antiporter activity | CLCN3,SLC7A10,CLCN4,SLC7A6,CLCN6,CLCN7,SLC47A2,SLC9A6A,SLC7A1,SLC35E4 |
Interacting Protein
SLC35D2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC35D2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC35D2.
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