SLC34A3

  • Official Full Name

    solute carrier family 34 (sodium phosphate), member 3

  • Overview

    This gene encodes a member of SLC34A transporter family of proteins, and is expressed primarily in the kidney. It is involved in transporting phosphate into cells via sodium cotransport in the renal brush border membrane, and contributes to the maintenance of inorganic phosphate concentration in the kidney. Mutations in this gene are associated with hereditary hypophosphatemic rickets with hypercalciuria. Alternatively spliced transcript variants varying in the 5 UTR have been found for this gene.

  • Synonyms

    SLC34A3;solute carrier family 34 (sodium phosphate), member 3;sodium-dependent phosphate transport protein 2C;FLJ38680;NPTIIc;naPi-2c;Na(+)/Pi cotransporter 2C;type IIc Na+/Pi cotransporter;sodium-phosphate transport protein 2C;Na(+)-dependent ph

Recombinant Proteins

  • Mouse
  • Rat
  • Human
  • Mammalian Cells
  • HEK293
  • His
  • DDK
  • Myc
  • Avi
  • Fc

    Involved Pathway

    SLC34A3 involved in several pathways and played different roles in them. We selected most pathways SLC34A3 participated on our site, such as SLC-mediated transmembrane transport,Sodium-coupled phosphate cotransporters,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC34A3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Transport of inorganic cations/anions and amino acids/oligopeptides SLC26A3.1,SLC43A1B,SLC34A2A,SLC12A1,SLC7A8A,SLC9A7,SLC5A8,SLC26A3.2,SLC17A7A,SLC6A19B
    Sodium-coupled phosphate cotransporters SLC20A1A,SLC20A1B,SLC20A2,SLC20A1,SLC34A2A
    SLC-mediated transmembrane transport SLC6A9,SLC28A2,SLC29A1A,CTNS,SLC7A6,SLCO2B1,SLC6A1A,SLC22A16,SLC38A5B,SLC15A3
    Type II Na+/Pi cotransporters SLC34A2A
    Transmembrane transport of small molecules AQP3B,SLC9A3.1,SLC5A4,SLC6A20B,ATP10A,SLC28A1,SLC35B3,RHCGA,ATP2B3A,SLC26A7

    Protein Function

    SLC34A3 has several biochemical functions, for example, sodium-dependent phosphate transmembrane transporter activity,sodium:phosphate symporter activity,symporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC34A3 itself. We selected most functions SLC34A3 had, and list some proteins which have the same functions with SLC34A3. You can find most of the proteins on our site.

    Function Related Protein
    sodium:phosphate symporter activity SLC17A2,SLC17A3,SLC20A1,SLC34A2,SLC17A4,SLC17A1,SLC20A2
    sodium-dependent phosphate transmembrane transporter activity SLC17A2,SLC17A3,SLC17A1,SLC17A4,SLC17A7A,SLC34A2A,SLC34A2B,SLC34A2,SLC17A7
    symporter activity SLC15A5,SLC17A7,SLC1A3B,SLC23A2,SLC15A4,SLC6A4A,SLC6A20A,SLC6A2,SLC6A1A,SLC38A1

    Interacting Protein

    SLC34A3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC34A3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC34A3.

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