SLC2A12
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Official Full Name
solute carrier family 2 (facilitated glucose transporter), member 12 -
Overview
SLC2A12 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion (Rogers et al., 2002). This family of transporters show conservation of 12 transmembrane helices as well as functionally significant amino acid residues (Joost and Thorens, 2001 [PubMed 11780753]).[supplied by OMIM, Mar 2008] -
Synonyms
SLC2A12;solute carrier family 2 (facilitated glucose transporter), member 12;GLUT8;GLUT12;solute carrier family 2, facilitated glucose transporter member 12;GLUT-12;glucose transporter type 12
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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| SLC2A12-10823Z | Recombinant Zebrafish SLC2A12 | Mammalian Cell | Zebrafish | His |
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| SLC2A12-930C | Recombinant Cynomolgus SLC2A12 Protein, His-tagged | Mammalian Cell | Cynomolgus | His |
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| SLC2A12-1627HCL | Recombinant Human SLC2A12 cell lysate | Human | Non |
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| SLC2A12-0937H | Recombinant Human SLC2A12 Full Length Transmembrane protein(Nanodisc) | HEK293 | Human | Non | Full L. |
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| SLC2A12-673C | Recombinant Cynomolgus Monkey SLC2A12 Protein, His (Fc)-Avi-tagged | HEK293 | Cynomolgus | His&Fc&Avi |
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| SLC2A12-673C-B | Recombinant Cynomolgus Monkey SLC2A12 Protein Pre-coupled Magnetic Beads | HEK293 | Cynomolgus |
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Involved Pathway
SLC2A12 involved in several pathways and played different roles in them. We selected most pathways SLC2A12 participated on our site, such as Facilitative Na+-independent glucose transporters,SLC-mediated transmembrane transport,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC2A12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | SLC6A7,SLC2A10,SLC22A7A,SLC39A10,SLC13A3,SLC6A20,SLC39A6,SLC6A19B,SLC41A1,SLC6A20B |
| Facilitative Na+-independent glucose transporters | SLC2A3,SLC2A15B,SLC2A15A,SLC2A10,SLC2A8,SLC2A6,SLC2A7 |
| Transmembrane transport of small molecules | TTYH1,SLC12A1,ANO8,ABCC9,ADD3A,ADD2,RHCGL1,SLC30A2,ATP1A1A.2,SLC34A3 |
| SLC-mediated transmembrane transport | SLC30A6,RHCG2A,SLC3A2B,SLC12A5B,SLCO2A1,SLC34A2A,SLC39A5,SLC6A1A,SLC30A3,SLC26A3 |
Protein Function
SLC2A12 has several biochemical functions, for example, substrate-specific transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC2A12 itself. We selected most functions SLC2A12 had, and list some proteins which have the same functions with SLC2A12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| substrate-specific transmembrane transporter activity | SLC22A13,HIAT1B,SLC2A8,SLC2A11L,SLC2A13B,SLC2A1A,SLC2A11B,SLC22A15,SLC2A15B,SLC2A13 |
Interacting Protein
SLC2A12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC2A12 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC2A12.
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References
- Fouz, N; Amid, A; et al. Gene Expression Analysis in MCF-7 Breast Cancer Cells Treated with Recombinant Bromelain. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 173:1618-1639(2014).
- Sharma, A; Aggarwal, J; et al. Stage Specific Expression of ATP-Binding Cassette and Solute Carrier Superfamily of Transporter Genes in Mammary Gland of Riverine Buffalo (Bubalus bubalis). ANIMAL BIOTECHNOLOGY 25:200-209(2014).
