SLC26A6
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Official Full Name
solute carrier family 26, member 6 -
Overview
This gene belongs to the solute carrier 26 family, whose members encode anion transporter proteins. This particular family member encodes a protein involved in transporting chloride, oxalate, sulfate and bicarbonate. Several alternatively spliced transcript variants of this gene, encoding distinct isoforms, have been described, but the full-length nature of some of these variants has not been determined. -
Synonyms
SLC26A6;solute carrier family 26, member 6;solute carrier family 26 member 6;anion transporter 1;DKFZp586E1422;pendrin L1;pendrin like protein 1;sulfate anion transporter;pendrin-L1;OTTHUMP00000210293;OTTHUMP00000210294;OTTHUMP00000210295;OTTHUMP00000210296;OTTHUMP00000210298;pendrin-like protein 1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC26A6-4559C | Recombinant Chicken SLC26A6 | Mammalian Cell | Chicken | His |
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| SLC26A6-1752HCL | Recombinant Human SLC26A6 293 Cell Lysate | HEK293 | Human | Non |
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| SLC26A6-2069H | Recombinant Human SLC26A6 Protein, His&GST-tagged | E.coli | Human | His&GST | Leu493-Leu759 |
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| Slc26a6-2070M | Recombinant Mouse Slc26a6 Protein, His-tagged | E.coli | Mouse | His | Phe477-Leu735 |
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Involved Pathway
SLC26A6 involved in several pathways and played different roles in them. We selected most pathways SLC26A6 participated on our site, such as Mineral absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC26A6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mineral absorption | MT2,ATP1A2,STEAP2,CLCN2,SLC26A9,CYBRD1,HMOX1,MT1G,HMOX2,TRPV6 |
Protein Function
SLC26A6 has several biochemical functions, for example, PDZ domain binding,anion:anion antiporter activity,bicarbonate transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC26A6 itself. We selected most functions SLC26A6 had, and list some proteins which have the same functions with SLC26A6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| oxalate transmembrane transporter activity | SLC26A5,SLC26A9,SLC26A3.2,SLC26A1,SLC26A2,SLC26A7,SLC26A4,SLC26A11,SLC26A6L,SLC26A3 |
| PDZ domain binding | LNX2,ACCN3,EXOC4,CXXC4,LPAR2,DLG4,KIF14,NLGN1,ATP2B2,ACOX1 |
| sulfate transmembrane transporter activity | SLC26A2,SLC26A11,SLC26A1,SLC26A3.2,SLC26A3.1,SLC26A9,SLC26A6L,SLC26A7,SLC26A3,SLC26A5 |
| protein binding | BSG,GRIP1,PPM1B,NDUFB11,MINK1,PPP1R13L,PPP1R16B,TOMM7,ICA1,ZC3HAV1 |
| secondary active sulfate transmembrane transporter activity | SLC26A3.2,SLC26A9,SLC26A3.1,SLC26A11,SLC26A6L,SLC13A1,SLC26A7,SLC26A1,SLC26A5,SLC26A4 |
| chloride channel activity | SLC26A11,GABRP,APOL1,SLC26A9,CLCNKB,SLC26A1,GABRR3,SLC26A3.2,CLIC1,SLC26A5 |
| chloride transmembrane transporter activity | SLC26A3,SLC4A1,Slc4a2,CFTR,SLC26A1,SLC26A4 |
| bicarbonate transmembrane transporter activity | SLC26A7,SLC4A1B,SLC26A11,SLC26A5,SLC4A11,SLC26A3,SLC26A2,SLC26A9,SLC26A3.2,SLC26A1 |
| anion:anion antiporter activity | SLC26A2,SLC4A8,SLC26A11,Slc4a2,SLC4A1B,SLC4A2A,SLC26A5,SLC26A6L,SLC26A4,SLC4A2B |
Interacting Protein
SLC26A6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC26A6 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC26A6.
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References
- Gregorio, SF; Carvalho, ESM; et al. Endocrine regulation of carbonate precipitate formation in marine fish intestine by stanniocalcin and PTHrP. JOURNAL OF EXPERIMENTAL BIOLOGY 217:1555-1562(2014).
- Abdulnour-Nakhoul, S; Nakhoul, HN; et al. Ion transport mechanisms linked to bicarbonate secretion in the esophageal submucosal glands. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 301:R83-R96(2011).
