SLC16A7

  • Official Full Name

    solute carrier family 16, member 7 (monocarboxylic acid transporter 2)

  • Overview

    This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as;lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of;monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed;in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in;multiple transcript variants.

  • Synonyms

    SLC16A7;solute carrier family 16, member 7 (monocarboxylic acid transporter 2);solute carrier family 16 (monocarboxylic acid transporters), member 7;monocarboxylate transporter 2;MCT2;MCT 2;solute carrier family 16 member 7

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • Chicken
  • Meriones unguiculatus (Mongolian jird) (Mongolian gerbil)
  • E.coli
  • Mammalian Cell
  • E.coli expression system
  • HEK293
  • His
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
SLC16A7-2700H Recombinant Human SLC16A7, His-tagged E.coli Human His C-46aa
SLC16A7-15237M Recombinant Mouse SLC16A7 Protein Mammalian Cell Mouse His
SLC16A7-3529Z Recombinant Zebrafish SLC16A7 Mammalian Cell Zebrafish His
SLC16A7-4416C Recombinant Chicken SLC16A7 Mammalian Cell Chicken His
RFL8219MF Recombinant Full Length Meriones Unguiculatus Monocarboxylate Transporter 2(Slc16A7) Protein, His-Tagged E.coli expression system Meriones unguiculatus (Mongolian jird) (Mongolian gerbil) His Full L. Full Length (1-71)
SLC16A7-8237M Recombinant Mouse SLC16A7 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
SLC16A7-8237M-B Recombinant Mouse SLC16A7 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    SLC16A7 involved in several pathways and played different roles in them. We selected most pathways SLC16A7 participated on our site, such as Proton-coupled monocarboxylate transport,SLC-mediated transmembrane transport,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC16A7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds SLC2A13B,SLC22A15,SLC13A5,SLC13A4,SLC6A20,SLC13A5A,SLC2A10,RHCGB,SLC13A2,SLC30A6
    SLC-mediated transmembrane transport SLC4A3,SLC35A3B,SLC7A3,SLC29A4,LCN12,SLC22A12,CP,SLC20A1B,SLC6A6A,SLC30A6
    Transmembrane transport of small molecules MIPB,RHAG,CLIC2,AQP9B,SLC17A7A,ASIC1A,TRPA1B,FXYD6,SLC35A2,SLC12A7
    Proton-coupled monocarboxylate transport SLC16A1,SLC16A8

    Protein Function

    SLC16A7 has several biochemical functions, for example, lactate transmembrane transporter activity,pyruvate secondary active transmembrane transporter activity,pyruvate transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC16A7 itself. We selected most functions SLC16A7 had, and list some proteins which have the same functions with SLC16A7. You can find most of the proteins on our site.

    Function Related Protein
    lactate transmembrane transporter activity SLC16A1,SLC16A3,SLC16A12,SLC5A12,SLC16A5,SLC16A8,SLC16A12B
    pyruvate transmembrane transporter activity BRP44,MPC1
    symporter activity SLC6A6A,SLC16A3,SLC25A3,SLC12A3,SLC6A11,SLC16A1,SLC17A7,SLC16A2,SLC24A4,PPP1R42

    Interacting Protein

    SLC16A7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC16A7 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC16A7.

    CPEB1

    Resources

    References

    • Merezhinskaya, N; Fishbein, WN; et al. Monocarboxylate transporters: Past, present, and future. HISTOLOGY AND HISTOPATHOLOGY 24:243-264(2009).

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