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SKIV2L2

Official Full Name

superkiller viralicidic activity 2-like 2
Overview

Superkiller viralicidic activity 2-like 2 is a protein that in humans is encoded by the SKIV2L2 gene.
Synonyms

SKIV2L2; superkiller viralicidic activity 2-like 2 (S. cerevisiae); KIAA0052; superkiller viralicidic activity 2-like 2; Dob1; fSAP118; functional spliceosome associated protein 118; Mtr4; ATP-dependent helicase SKIV2L2; functional spliceosome-associated;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SKIV2L2-2690H	Recombinant Human SKIV2L2, His-tagged	E.coli	His	3-307aa	$319 / 25μg
Mouse	SKIV2L2-15185M	Recombinant Mouse SKIV2L2 Protein	Mammalian Cell	His		Inquiry
Mouse	SKIV2L2-8202M-B	Recombinant Mouse SKIV2L2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	SKIV2L2-8202M	Recombinant Mouse SKIV2L2 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Zebrafish	SKIV2L2-12785Z	Recombinant Zebrafish SKIV2L2	Mammalian Cell	His		Inquiry
Chicken	SKIV2L2-2156C	Recombinant Chicken SKIV2L2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

SKIV2L2 involved in several pathways and played different roles in them. We selected most pathways SKIV2L2 participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SKIV2L2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
RNA degradation	DIS3;PAN3;PATL1;LSM5;PAPD7;WDR61;EXOSC8;PABPC3;PNPT1

SKIV2L2 has several biochemical functions, for example, ATP binding, RNA helicase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SKIV2L2 itself. We selected most functions SKIV2L2 had, and list some proteins which have the same functions with SKIV2L2. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	CSNK1D;ABCB4;CSNK1A1;SBK1;NME1;STRADB;KTI12;CSNK1E;PAPSS2B
RNA helicase activity	DHX15;DDX10;DDX5;UAP1L1;DDX24;SKIV2L2;RAD54B;CTU1;PRIM2
poly(A) RNA binding	SNRPD3;TNRC6B;EEF1A1;RPL12;POLRMT;KIAA1429;MRPL13;DDX5;DDX47
protein binding	EP300;SP1;NCL;PLSCR3;FASTK;LINGO1;SMARCAL1;ALAS2;FBXW2

SKIV2L2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SKIV2L2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SKIV2L2.

MPHOSPH6; PPP2R2B; YWHAG; PBX2; UPF2; midostaurin; ssrna_ug

Research Area

Yoneyama, S; Sakurada, Y; et al. Genetic Variants in the SKIV2L Gene in Exudative Age-related Macular Degeneration in the Japanese Population. OPHTHALMIC GENETICS 35:151-155(2014).

Lu, F; Shi, Y; et al. A Genetic Variant in the SKIV2L Gene Is Significantly Associated With Age-Related Macular Degeneration in a Han Chinese Population. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 54:2911-2917(2013).