SHF
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Official Full Name
Src homology 2 domain containing F -
Overview
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling. -
Synonyms
MGC126650;MGC126652;SH2 domain-containing adapter protein F;SHF
Recombinant Proteins
- Human
- Mouse
- Fruit fly
- E.coli
- Mammalian Cell
- HEK293T
- HEK293
- His
- N-His&C-Myc
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SHF-2658H | Recombinant Human SHF, His-tagged | E.coli | Human | His | 195-378aa | |
| SHF-15098M | Recombinant Mouse SHF Protein | Mammalian Cell | Mouse | His |
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| shf-3927F | Recombinant Fruit fly shf protein(31-456aa), His&Myc-tagged | E.coli | Fruit fly | N-His&C-Myc | 31-456aa |
|
| SHF-4691H | Recombinant Human SHF Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Shf-5860M | Recombinant Mouse Shf Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| SHF-8149M | Recombinant Mouse SHF Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
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| SHF-8149M-B | Recombinant Mouse SHF Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
SHF involved in several pathways and played different roles in them. We selected most pathways SHF participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SHF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SHF has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by SHF itself. We selected most functions SHF had, and list some proteins which have the same functions with SHF. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | TNNI1B,TPRG,GM5136,CCDC149A,DIA1A,ZPLD1,TMEM26B,GM4220,AGPHD1,ZPCX |
Interacting Protein
SHF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHF here. Most of them are supplied by our site. Hope this information will be useful for your research of SHF.
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References
- Yang, YP; Li, HR; et al. Second heart field and the development of the outflow tract in human embryonic heart. DEVELOPMENT GROWTH & DIFFERENTIATION 55:359-367(2013).
- Liang, S; Li, HC; et al. Pulmonary endoderm, second heart field and the morphogenesis of distal outflow tract in mouse embryonic heart. DEVELOPMENT GROWTH & DIFFERENTIATION 56:276-292(2014).
