SHC4

Official Full Name

SHC (Src homology 2 domain containing) family, member 4
Synonyms

SHC4;SHC (Src homology 2 domain containing) family, member 4;SHC-transforming protein 4;rai like protein;RaLP;hShcD;MGC34023;SH2 domain protein C4;SHC (Src homology 2 domain containing) family member 4;SHC 4;SHC;SHC family member 4;SHC transforming protein 4;SHC transforming protein D;SHCD;Src homology 2 domain containing familymember 4;Src homology 2 domain containing transforming protein C4;rai-like protein;OTTHUMP00000162250;SHC-transforming protein D;src homology 2 domain-containing-transforming protein C4

Recombinant Proteins

Type:

Recombinant Proteins

Cell & Tissue Lysates

Protein Pre-coupled Magnetic Beads

Filters:

Species

Human
Mouse

Source

E.coli
Mammalian Cells
HEK293

Tag

Cat.#	Product name	Source (Host)	Species	Tag	Protein Length	Price
SHC4-2656H	Recombinant Human SHC4, GST-tagged	E.coli	Human	GST	C-term-307aa	$319 / 25μg
SHC4-15093M	Recombinant Mouse SHC4 Protein	Mammalian Cells	Mouse	His		Inquiry
SHC4-1861HCL	Recombinant Human SHC4 293 Cell Lysate	HEK293	Human	Non		Inquiry
SHC4-355H	Recombinant Human SHC4 Protein, MYC/DDK-tagged, C13 and N15-labeled	HEK293	Human	DDK&Myc		Inquiry
Shc4-5855M	Recombinant Mouse Shc4 Protein, Myc/DDK-tagged	HEK293	Mouse	DDK&Myc		Inquiry
SHC4-8144M	Recombinant Mouse SHC4 Protein, His (Fc)-Avi-tagged	HEK293	Mouse	Avi&Fc&His		Inquiry
SHC4-8144M-B	Recombinant Mouse SHC4 Protein Pre-coupled Magnetic Beads	HEK293	Mouse			Inquiry

Involved Pathway

SHC4 involved in several pathways and played different roles in them. We selected most pathways SHC4 participated on our site, such as ErbB signaling pathway,Ras signaling pathway,Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Chronic myeloid leukemia	SHC1,CRKL,TGFB2,BRAF,CTBP1,BCL2L1,CTBP2,RUNX1,CBL,HDAC2
Neurotrophin signaling pathway	RAPGEF1,KIDINS220,PRDM4,NGFR,NTRK2,MAPK10,ABL1,MAP3K3,ZFP110,FOXO3
Natural killer cell mediated cytotoxicity	TYROBP,PRKCB,Raet1c,KIR2DL1,PRKCG,Casp3,FCGR4,IFNB1,IFNGR2,HCST
Prolactin signaling pathway	MAPK12,PIK3R1,ESR2,SLC2A2,NEK3,NFKB1,CCND1,KRAS,INS2,TNFSF11
Chemokine signaling pathway	PF4,PIK3R1,ROCK2,GNAI1,GNB1,GNG13,CRKL,KRAS,CX3CR1,CXCL16
Focal adhesion	RAC3A,ITGA8,TNN,FN1A,PIK3CB,VEGFAB,PDGFB,STYK1,PPP1R12B,SPP1
Glioma	BRAF,CAMK2G,HRAS,IGF1,PTEN,TRP53,CALML5,ARAF,RB1,MAPK1
MicroRNAs in cancer	KIF23,PLCG2,PRKCA,DNMT3A,CD44,TNXB,CCNE1,RASSF1,CCND1,CYP24A1
Alcoholism	HIST2H2AA4,HIST1H2BF,H2AFZ,H3F3C,GNG4,HIST1H2AG,GRIN2C,MAOB,HAT1,GRIN2B

Protein Function

SHC4 has several biochemical functions, for example, protein binding,protein domain specific binding,protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHC4 itself. We selected most functions SHC4 had, and list some proteins which have the same functions with SHC4. You can find most of the proteins on our site.

Function	Related Protein
receptor tyrosine kinase binding	PTPN14,ANGPT2A,PIK3R2,FLT3LG,TP53,ANGPT1,SOCS5,PTPN11,LRP4,NCK1
protein binding	PELI2,DCP2,TCEB1,TTC19,LOX,FAM113B,PMM2,RPS20,BRSK1,NDUFB9
protein domain specific binding	EHD2,STX1A,ZBTB16,NFE2L2,CASKIN1,TH,YWHAE1,RAB6A,RHOA,CHMP1B
protein kinase binding	RB1CC1,AXIN1,EEF1A2,DNM2,FGF19,CDC42,PRKAG2,AGTR1A,AP2A2,SKAP1

Interacting Protein

SHC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHC4.

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