SH3GLB1
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Official Full Name
SH3-domain GRB2-like endophilin B1 -
Overview
This gene encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. This protein may also be involved in maintaining mitochondrial morphology. Alternate splicing results in multiple transcript variants. -
Synonyms
SH3GLB1;SH3-domain GRB2-like endophilin B1;SH3 domain, GRB2 like, endophilin B1;endophilin-B1;Bif 1;CGI 61;KIAA0491;PPP1R70;protein phosphatase 1;regulatory subunit 70;Bax-interacting factor 1;SH3-containing protein SH3GLB1;SH3 domain-containi
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- GST
- Myc&DDK
Involved Pathway
SH3GLB1 involved in several pathways and played different roles in them. We selected most pathways SH3GLB1 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SH3GLB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | HLA-G,KIF5A,ARRB2A,TGFB1A,ARF3,CHMP2A,RAB35,EHD2,SH3GLB2B,GRK7B |
Protein Function
SH3GLB1 has several biochemical functions, for example, identical protein binding,lipid binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SH3GLB1 itself. We selected most functions SH3GLB1 had, and list some proteins which have the same functions with SH3GLB1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| identical protein binding | PTEN,GRIN3A,TPRGL,TMEM173,SID4,KHDC1B,HCN4,MTPAP,PIP4K2C,RELA |
| protein homodimerization activity | HMGCS1,KIF20B,SQSTM1,RELA,ABCD3,NADK2,HMGCR,FGFR1OP2,DMRTB1,DMRT1 |
| lipid binding | APOA1B,BAX,PFN3,UNC119.1,Alb,BPIFA5,FABP12,C3,MARK2,CRABP2B |
| protein binding | PLK1,RBM39,C16orf59,OAS1A,AP4B1,EPN1,TOP3A,PCDH17,ATG14,C1orf216 |
Interacting Protein
SH3GLB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SH3GLB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SH3GLB1.
SH3GLB2;UVRAG
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