SGPP2
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Official Full Name
sphingosine-1-phosphate phosphotase 2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SGPP2-15044M | Recombinant Mouse SGPP2 Protein | Mammalian Cell | Mouse | His |
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| SGPP2-8108M | Recombinant Mouse SGPP2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SGPP2-8108M-B | Recombinant Mouse SGPP2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SGPP2 involved in several pathways and played different roles in them. We selected most pathways SGPP2 participated on our site, such as Sphingolipid metabolism,Sphingolipid signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGPP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Sphingolipid signaling pathway | MAPK11,BAX,PPP2CA,MS4A2,S1PR2,PPP2R2A,NOS3,PIK3R1,SGPP1,PLCB1 |
| Sphingolipid metabolism | R05D11.9,CERS5,SMPD5,NEU3.1,LASS1,PPM1L,GALCA,CERS3B,NEU3.3,SMPD2 |
Protein Function
SGPP2 has several biochemical functions, for example, 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity,IDP phosphatase activity,JUN kinase phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SGPP2 itself. We selected most functions SGPP2 had, and list some proteins which have the same functions with SGPP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity | TENC1,PIKFYVE,CTDSPL2A,FIG4,PTPRQ,NT5DC3,CTDSPL2B,PXYLP1,SACM1L,SACM1LB |
| sphingosine-1-phosphate phosphatase activity | PPAP2B,SGPP1 |
| MAP kinase tyrosine/serine/threonine phosphatase activity | PXYLP1,PTPRQ,DUSP8A,SACM1LA,DUSP5,DUSP7,DUSP21,DUSP1,SACM1L,DUSP14 |
| IDP phosphatase activity | SACM1L,SACM1LB,NT5DC3,PXYLP1,TENC1,CTDSPL2B,CTDSPL2A,PTPRQ,SACM1LA |
| inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity | ITPK1,NT5DC3,PXYLP1,CTDSPL2B,CTDSPL2A,PTPRQ,SACM1LB,TENC1,SACM1L,SACM1LA |
| inositol-1,3,4-trisphosphate 1-phosphatase activity | SACM1LA,PXYLP1,INPP1,SACM1LB,NT5DC3,SACM1L,TENC1,PTPRQ,CTDSPL2A,CTDSPL2B |
| JUN kinase phosphatase activity | PXYLP1,SACM1LA,SACM1L,NT5DC3,CTDSPL2B,CTDSPL2A,DUSP19,TENC1,SACM1LB,PTPRQ |
| phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity | CTDSPL2B,MTMR1,MTMR1B,PTPRQ,MTM1,SACM1LA,MTMR3,CTDSPL2A,NT5DC3,MTMR8 |
| transmembrane receptor protein phosphatase activity | TENC1,SACM1L,NT5DC3,PTPRQ,PXYLP1,CTDSPL2B,CTDSPL2A,SACM1LA,SACM1LB |
Interacting Protein
SGPP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SGPP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SGPP2.
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References
- Reardon, BJ; Hansen, JG; et al. Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function. BMC MEDICAL GENETICS 14:-(2013).
- Abuhusain, HJ; Matin, A; et al. A Metabolic Shift Favoring Sphingosine 1-Phosphate at the Expense of Ceramide Controls Glioblastoma Angiogenesis. JOURNAL OF BIOLOGICAL CHEMISTRY 288:37355-37364(2013).
