SERPINA3G
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Official Full Name
Serine (or cysteine) Peptidase InhibitorClade A, Member 3G -
Overview
Spi2A is a serine and cysteine protease inhibitor. It can inhibit lysosomal papain-like proteases including the cathepsins B, G, H, K, L and V. It is ineffective against elastase, granzyme A, granzyme B, or caspases 3, 8 or 9. Inhibition of cytoplasmic cathepsin B following release from the lysosome may protect cells from apoptosis. This may facilitate the survival of progenitor T-cells and the subsequent development of long term memory CD8 T-cells. -
Synonyms
Serpina3g;2A2;spi2;Spi2A;Spi2-1;AI119734;Spi2/eb.1;serine protease inhibitor A3G;serpin 2A;serpin A3G;alpha-1 antiproteinase;serine protease inhibitor 2A;serine protease inhibitor 2-1;serine (or cysteine) proteinase inhibitor, clade A, member 3G
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Involved Pathway
SERPINA3G involved in several pathways and played different roles in them. We selected most pathways SERPINA3G participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SERPINA3G were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
SERPINA3G has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SERPINA3G itself. We selected most functions SERPINA3G had, and list some proteins which have the same functions with SERPINA3G. You can find most of the proteins on our site.
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Interacting Protein
SERPINA3G has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SERPINA3G here. Most of them are supplied by our site. Hope this information will be useful for your research of SERPINA3G.
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