SEPN1
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Official Full Name
selenoprotein N, 1 -
Overview
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3 UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Mutations in this gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. -
Synonyms
SEPN1;selenoprotein N, 1;MDRS1, rigid spine muscular dystrophy 1 , RSMD1;selenoprotein N;RSS;selN;SELN_HUMAN;MDRS1;RSMD1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SEPN1-1237Z | Recombinant Zebrafish SEPN1 | Mammalian Cell | Zebrafish | His |
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| SEPN1-3826C | Recombinant Chicken SEPN1 | Mammalian Cell | Chicken | His |
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Involved Pathway
SEPN1 involved in several pathways and played different roles in them. We selected most pathways SEPN1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SEPN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SEPN1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SEPN1 itself. We selected most functions SEPN1 had, and list some proteins which have the same functions with SEPN1. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
SEPN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEPN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SEPN1.
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