SELS
-
Official Full Name
selenoprotein S -
Overview
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3 UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. -
Synonyms
SELS;selenoprotein S;VCP-interacting membrane protein;VIMP;ADO15;SBBI8;SEPS1;AD-015
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SELS-2573H | Recombinant Human SELS, GST-tagged | E.coli | Human | GST | 1-189aa | |
| SELS-1983HCL | Recombinant Human SELS 293 Cell Lysate | HEK293 | Human | Non |
|
Involved Pathway
SELS involved in several pathways and played different roles in them. We selected most pathways SELS participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with SELS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein processing in endoplasmic reticulum | PDIA4,UBE2G2,STT3B,TXNDC5,ERO1LB,SEC24C,SVIP,RPN1,PPP1R15A,UBE2D1A |
Protein Function
SELS has several biochemical functions, for example, ATPase binding,antioxidant activity,enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SELS itself. We selected most functions SELS had, and list some proteins which have the same functions with SELS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin-specific protease binding | AMFR,SYVN1,SART3,VCP,RAD23A,MARCH6,BAG6,VPS24,DERL1,CHMP3 |
| protein binding | CBY1,FDXR,ALDOB,NR2C2,ZNF26,NKX3,WDR11,RPL27A,ELOVL6,CNST |
| receptor activity | CCR6,NEO1,ITGB3B,GRIA4B,RTN4R,RET,SV2A,NLGN3A,TLR3,TLR6 |
| enzyme binding | GRIN1,WWOX,UBE4B,HSPA6,UGT1A4,CCDC99,PLSCR4,AXIN1,HOXA9,GOLPH3 |
| antioxidant activity | SEPW1,UBIAD1,PRDX2,APOE,S100A9,TP53INP1,FABP1,APOA4,FAM213AA,APOM |
| ATPase binding | ATP6V0A4,ZNHIT6,ATP6V0A1A,METTL21A,CHMP4A,NOP58,DERL1,ATXN3,SNX10,PLN |
Interacting Protein
SELS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SELS here. Most of them are supplied by our site. Hope this information will be useful for your research of SELS.
Resources
Related Services
Related Products
References
