SDS

  • Official Full Name

    serine dehydratase

  • Overview

    This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver.

  • Synonyms

    SDS;serine dehydratase;L-serine dehydratase/L-threonine deaminase;SDH;L serine deaminase;TDH;L-serine deaminase;OTTHUMP00000241529;L-serine dehydratase;L-serine ammonia-lyase;L-threonine dehydratase

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Rat
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • His
  • Non
  • DDK
  • Myc
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
SDS-2555H Recombinant Human SDS, His-tagged E.coli Human His 1-218aa
SDS-4118R Recombinant Rhesus monkey SDS Protein, His-tagged Mammalian Cells Rhesus macaque His
SDS-5295R Recombinant Rat SDS Protein Mammalian Cells Rat His
SDS-2004HCL Recombinant Human SDS 293 Cell Lysate HEK293 Human Non
SDS-2621H Recombinant Human SDS Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
SDS-3935R Recombinant Rhesus Macaque SDS Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
SDS-3935R-B Recombinant Rhesus Macaque SDS Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
SDS-4954R Recombinant Rat SDS Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
SDS-4954R-B Recombinant Rat SDS Protein Pre-coupled Magnetic Beads HEK293 Rat
SDS-5644H Recombinant Human SDS protein, His&Myc-tagged E.coli Human His&Myc 1-328aa
Sds-5737M Recombinant Mouse Sds Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc

    Involved Pathway

    SDS involved in several pathways and played different roles in them. We selected most pathways SDS participated on our site, such as Biosynthesis of amino acids,Biosynthesis of antibiotics,Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with SDS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycine, serine and threonine metabolism GLDC,PGAM1A,SHMT1,PSAT1,DAO.2,BHMT,CTH,GCSHA,AOC3,GNMT
    Biosynthesis of amino acids GOT1,PKMB,PYCR1B,PRPS1B,GAPDH,PRPS2,ENO2,CS,IDH3A,SHMT2
    Cysteine and methionine metabolism BHMT,LDHBA,DNMT1,BCAT2,LDHB,MAT2AB,LDHBB,MDH1,GCLC,CDO1
    Metabolic pathways FUT8,AGXT2L2,NME5,GLS2,GAPDH,TYRP1B,IDS,GATB,ASPA,NDUFA8
    Biosynthesis of antibiotics pykF,AKR1A1,DLD,GPR19,SDSL,ACAA2,UAP1L1,ANI_1_2390104,AK7,ADH5
    L-serine degradation SDSL
    Carbon metabolism ME1,PGLS,FBP1A,PGK2,GPI1,PGP,ME3,HK2,AGXTA,PRPS2
    L-threonine degradation V DBT,SDSL

    Protein Function

    SDS has several biochemical functions, for example, L-serine ammonia-lyase activity,L-threonine ammonia-lyase activity,protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SDS itself. We selected most functions SDS had, and list some proteins which have the same functions with SDS. You can find most of the proteins on our site.

    Function Related Protein
    L-serine ammonia-lyase activity SDSL,SRR
    protein homodimerization activity TENM1,DMRT2A,NR6A1,UGT1A1,ABCD2,CASQ2,GRIK1,TBX1,OLFM4,TFAP4
    pyridoxal phosphate binding PYGMB,CBSA,PROSC,Alb,MARC1,GPT,PYGMA,SPTLC3,GAD1,DDC
    L-threonine ammonia-lyase activity SDSL

    Interacting Protein

    SDS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SDS here. Most of them are supplied by our site. Hope this information will be useful for your research of SDS.

    Resources

    References

    • Song, YN; Li, ZX; et al. Effect of malondialdehyde treatment on the IgE binding capacity and conformational structure of shrimp tropomyosin. FOOD CHEMISTRY 175:374-380(2015).
    • Nipate, SS; Hurali, PB; et al. Evaluation of anti-inflammatory, anti-nociceptive, and anti-arthritic activities of Indian Apis dorsata bee venom in experimental animals: biochemical, histological, and radiological assessment. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY 37:171-184(2015).

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