SDR16C5

  • Official Full Name

    short chain dehydrogenase/reductase family 16C, member 5

  • Overview

    RDHE2 belongs to a family of short-chain alcohol dehydrogenases/reductases that catalyze the first and rate-limiting;step that generates retinaldehyde from retinol (Matsuzaka et al., 2002 (PubMed 12372410)).

  • Synonyms

    SDR16C5;short chain dehydrogenase/reductase family 16C, member 5;epidermal retinol dehydrogenase 2;RDH E2;RDHE2;EPHD 2;EPHD2;Epidermal retinal dehydrogenase 2;FLJ33105;RDH#2;Retinal short chain dehydrogenase reductase 2;Retinal short chain dehydrogenase reductase;Short chain dehydrogenase/reductase family 16C member 5;EPHD-2;retSDR2;retinal short-chain dehydrogenase reductase 2;short-chain dehydrogenase/reductase family 16C member 5;RDH-E2

Recombinant Proteins

  • Mouse
  • Chicken
  • Rhesus macaque
  • Human
  • Mus musculus
  • Mammalian Cells
  • E.coli
  • HEK293
  • Human Cells
  • His
  • Non
  • Flag
  • DDK
  • Myc
  • Avi
  • Fc

    Involved Pathway

    SDR16C5 involved in several pathways and played different roles in them. We selected most pathways SDR16C5 participated on our site, such as RA biosynthesis pathway,Retinol metabolism,Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with SDR16C5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Retinol metabolism CYP2B19,UGT2A3,UGT1A6,UGT1AB,CYP4A12A,ALDH1A2,CYP2C50,CYP2C39,UGT2A1,CYP26C1
    RA biosynthesis pathway DHRS9,DHRS3A,AKR1C21,CRABP1,RDH14A,AKR1C6,ADH8A,RDH10,CRABP1B,RDH7
    retinoate biosynthesis I RBP5
    Signaling by Retinoic Acid PDK3B,DHRS3A,PDK2B,DHRS9,CRABP1A,RDH10,RARGA,RDH14A,RDH7,RDH14
    Signal Transduction LPAR5A,PRLRB,CUL5A,PYGO2,PRLH,ARHGAP6,GDI2,RXFP2B,HCRT,RNF146

    Protein Function

    SDR16C5 has several biochemical functions, for example, retinol dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SDR16C5 itself. We selected most functions SDR16C5 had, and list some proteins which have the same functions with SDR16C5. You can find most of the proteins on our site.

    Function Related Protein
    retinol dehydrogenase activity RDH12,ADH7,BMP2,SDR9C7,AKR1C3,RDH7,HSD17B6,DHRS3,RDH8,ADH1

    Interacting Protein

    SDR16C5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SDR16C5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SDR16C5.

    EXTL1;NLK

    Resources

    References

    • Chen, HZ; Fang, X; et al. Gene expression profile analysis for different idiopathic interstitial pneumonias subtypes. EXPERIMENTAL LUNG RESEARCH 40:367-379(2014).
    • Bai, H; Zhu, J; et al. Identification of Genes Related to Beak Deformity of Chickens Using Digital Gene Expression Profiling. PLOS ONE 9:-(2014).

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