SDHAF2
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Official Full Name
succinate dehydrogenase complex assembly factor 2 -
Overview
This gene encodes a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. Mutations in this gene are associated with paraganglioma. -
Synonyms
SDHAF2;succinate dehydrogenase complex assembly factor 2;C11orf79, chromosome 11 open reading frame 79 , paraganglioma or familial glomus tumors 2 , PGL2;succinate dehydrogenase assembly factor 2, mitochondrial;FLJ20487;SDH5;mitochondrial;Chromosome 11 open reading frame 79;hSDH5;Paraganglioma or familial glomus tumors 2;PGL2;SDH assembly factor 2;SDHF2_HUMAN;Succinate dehydrogenase assembly factor 2;Succinate dehydrogenase subunit 5;succinate dehydrogenase subunit 5, mitochondrial;C11orf79
Recombinant Proteins
- Mouse
- Rhesus macaque
- Zebrafish
- Rat
- Human
- Cynomolgus
- Mammalian Cell
- E.coli
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
SDHAF2 involved in several pathways and played different roles in them. We selected most pathways SDHAF2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SDHAF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SDHAF2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SDHAF2 itself. We selected most functions SDHAF2 had, and list some proteins which have the same functions with SDHAF2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | UBE2E2,RD3,RLTPR,SETX,MID2,MAP3K8,FAM123A,GMIP,CCNB3,EIF2B5 |
Interacting Protein
SDHAF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SDHAF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SDHAF2.
IKBKAP;EEF1A1;IMMT;CCDC90B;HSPA8;CTNNA2;SDHA;RRM2;HSPA9;SLC1A5;CWF19L2;NOL8;CORO2A;ABCA2;SSX2IP;KLHDC2
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References
- Rutter, J; Hughes, AL; et al. Power(2): The power of yeast genetics applied to the powerhouse of the cell. TRENDS IN ENDOCRINOLOGY AND METABOLISM 26:59-68(2015).
- Boedeker, CC; Hensen, EF; et al. Genetics of hereditary head and neck paragangliomas. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK 36:907-916(2014).
