SAMM50
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Official Full Name
sorting and assembly machinery component 50 homolog (S. cerevisiae) -
Overview
This gene encodes a component of the Sorting and Assembly Machinery (SAM) of the mitochondrial outer membrane. The Sam complex functions in the assembly of beta-barrel proteins into the outer mitochondrial membrane. -
Synonyms
SAMM50;sorting and assembly machinery component 50 homolog (S. cerevisiae);sorting and assembly machinery component 50 homolog;CGI 51;OMP85;TOB55;TRG 3;YNL026W;OTTHUMP00000197826;sorting and assembly machinery 50kDa;transformation-related gene 3 protein;SAM50;TRG-3;CGI-51
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rhesus macaque
- Rat
- Chicken
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
Involved Pathway
SAMM50 involved in several pathways and played different roles in them. We selected most pathways SAMM50 participated on our site, such as Metabolism of proteins,Mitochondrial protein import, which may be useful for your reference. Also, other proteins which involved in the same pathway with SAMM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitochondrial protein import | SLC25A12,TOMM6,DNAJC19,TIMM44,TIMM17B,GFER,TOMM20,MTX1,PAM16,FXC1 |
| Metabolism of proteins | GALNTL2,GALNT6,EXOC5,FBXW4,GPR119,PAPPA,TMED2,SLC38A8,DDOST,DPP4 |
Protein Function
SAMM50 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SAMM50 itself. We selected most functions SAMM50 had, and list some proteins which have the same functions with SAMM50. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CHGB,SPAT-1,E2F7,C1orf187,SUGT1,PQBP1,PRKD3,ACVR1,RHOA,PTPRS |
Interacting Protein
SAMM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SAMM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of SAMM50.
CHCHD3;Erh;MEOX2;idh;menA;MTX2;Mtx2;MTX1;IMMT;TIMMDC1
Resources
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References
- Kitamoto, T; Kitamoto, A; et al. Targeted next-generation sequencing and fine linkage disequilibrium mapping reveals association of PNPLA3 and PARVB with the severity of nonalcoholic fatty liver disease. JOURNAL OF HUMAN GENETICS 59:241-246(2014).
- Liu, LY; Fox, CS; et al. Functional validation of GWAS gene candidates for abnormal liver function during zebrafish liver development. DISEASE MODELS & MECHANISMS 6:1271-1278(2013).
