SALL1
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Official Full Name
spalt-like transcription factor 1 -
Overview
The protein encoded by this gene is a zinc finger transcriptional repressor and may be part of the NuRD histone deacetylase complex (HDAC). Defects in this gene are a cause of Townes-Brocks syndrome (TBS) as well as bronchio-oto-renal syndrome (BOR). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] -
Synonyms
SALL1;spalt-like transcription factor 1;TBS;HSAL1;Sal-1;ZNF794;HEL-S-89;sal-like protein 1;zinc finger protein 794;zinc finger protein SALL1;zinc finger protein Spalt-1;epididymis secretory protein Li 89
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SALL1-6272C | Recombinant Chicken SALL1 | Mammalian Cell | Chicken | His |
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| SALL1-2075HCL | Recombinant Human SALL1 293 Cell Lysate | HEK293 | Human | Non |
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Involved Pathway
SALL1 involved in several pathways and played different roles in them. We selected most pathways SALL1 participated on our site, such as Wnt Signaling Pathway NetPath, which may be useful for your reference. Also, other proteins which involved in the same pathway with SALL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Wnt Signaling Pathway NetPath | MTAP1B,NR5A1,CSNK2A1P,TAX1BP3,ANKRD6,BCL9,TFAP2A,MAP1B,BRD7,PAX2 |
Protein Function
SALL1 has several biochemical functions, for example, DNA binding,RNA polymerase II core promoter proximal region sequence-specific DNA binding,beta-catenin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SALL1 itself. We selected most functions SALL1 had, and list some proteins which have the same functions with SALL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sequence-specific DNA binding | FOXI3B,EOMES,PAX3,POU3F3B,MAF,MAFF,HOXA6,NR1H5,ZNF35,DLX4 |
| DNA binding | Alb,DNASE1L2,LIN28B,ZNF48,HER2,ETV5A,CENPW,EBF2,XBP1,FOXB1A |
| transcription regulatory region DNA binding | WNT1,IKZF2,ZNF335,ZFP335,DLX5,HINFP,FOXC2,GABPA,GATA6,TNF |
| transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | ETS2,BCL11AA,PPARA,TCF3,BCL11AB,MXD1,CC2D1A,YY1,NEUROG3,TGIF1 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | MYBL2,TP73,ZNF253,TBX3,Ar,AGO1,GZF1,RBPJA,MITF,MAFA |
| chromatin binding | TP73,GLI2,CENPA,PRMT6,TOX2,NFATC2,GLI1,ANKRD2,PBX2,MBD1 |
| metal ion binding | RC3H2,ZNF397,CASZ1,LIMS2,UBE3A,ZNF777,TRP63,RNF222,ATP2A3,ROCK2 |
| contributes_to histone deacetylase activity | BRMS1L,BRMS1LA,SUDS3,SIN3AA,BRMS1,SIN3A,SIN3B |
| beta-catenin binding | TAX1BP3,DACT2,SMAD3,TBL1X,TBL1XR1,APC2,TCF7L2,GLI3,CBY1,PROP1 |
Interacting Protein
SALL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SALL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SALL1.
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