RXFP3
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Official Full Name
relaxin/insulin-like family peptide receptor 3 -
Overview
Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation. -
Synonyms
RXFP3;relaxin/insulin-like family peptide receptor 3;SALPR;RLN3R1;RXFPR3;GPCR135;relaxin-3 receptor 1;RLN3 receptor 1;relaxin 3 receptor 1;G-protein coupled receptor SALPR;g protein-coupled receptor SALPR;relaxin family peptide receptor 3;G-protein coupled receptor GPCR135;somatostatin and angiotensin-like peptide receptor;somatostatin- and angiotensin-like peptide receptor
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RXFP3-2478H | Recombinant Human RXFP3, GST-tagged | E.coli | Human | GST | 1-92aa | |
| RXFP3-7042Z | Recombinant Zebrafish RXFP3 | Mammalian Cell | Zebrafish | His |
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| RXFP3-1553HCL | Recombinant Human RXFP3 cell lysate | Human | Non |
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| RFL21907HF | Recombinant Full Length Human Relaxin-3 Receptor 1(Rxfp3) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-469) |
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| RFL6922MF | Recombinant Full Length Mouse Relaxin-3 Receptor 1(Rxfp3) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-472) |
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Involved Pathway
RXFP3 involved in several pathways and played different roles in them. We selected most pathways RXFP3 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with RXFP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | TAAR1,CHRM5B,GRIK4,P2RX7,PRL,GRIA4B,TAAR6,IL12,HTR1B,HTR1AA |
Protein Function
RXFP3 has several biochemical functions, for example, G-protein coupled peptide receptor activity,G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RXFP3 itself. We selected most functions RXFP3 had, and list some proteins which have the same functions with RXFP3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled peptide receptor activity | CYSLTR2,CYSLTR1,GPR37,LTB4R2,LTB4R,GPR37L1,TSHR,MCHR2,NPR1,LHCGR |
| G-protein coupled receptor activity | GPR55A,F2RL1.2,OLFR488,TMTOPS2B,TAAR7B,GNRHR1,AGTR1B,FZD7A,GPR56,PROKR1A |
Interacting Protein
RXFP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RXFP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RXFP3.
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References
- Liu, Y; Song, G; et al. Quantitative measurement of cell membrane receptor internalization by the nanoluciferase reporter: Using the G protein-coupled receptor RXFP3 as a model. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1848:688-694(2015).
- Hosken, IT; Sutton, SW; et al. Relaxin-3 receptor (Rxfp3) gene knockout mice display reduced running wheel activity: Implications for role of relaxin-3/RXFP3 signalling in sustained arousal. BEHAVIOURAL BRAIN RESEARCH 278:167-175(2015).
