RTCD1
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Official Full Name
RNA terminal phosphate cyclase domain 1 -
Overview
This gene encodes a member of the RNA 3-phosphate cyclase family. The encoded protein plays a role in RNA metabolism;by catalyzing the ATP-dependent conversion of the 3-phosphate of RNA substrates to a 2,3-cyclic phosphodiester.;Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. -
Synonyms
RTCD1;RNA terminal phosphate cyclase domain 1;RTC domain containing 1;RNA 3-terminal phosphate cyclase;RPC;2310009A18Rik;AI450277;EC 6.5.1.4;MGC102342;MGC94866;RNA 3 terminal phosphate cyclase;RNA 3-prime-terminal phosphate cyclase;RNA cyclase;RNA terminal phosphate cyclase domain containing protein 1;RNA-3-phosphate cyclase;RPC1;RTC domain containing protein 1;RTC1;phosphate cyclase;RTC domain-containing protein 1;RNA terminal phosphate cyclase domain-containing protein 1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RTCD1-2457H | Recombinant Human RTCD1, His-tagged | E.coli | Human | His | 1-379aa | |
| RTCD1-14560M | Recombinant Mouse RTCD1 Protein | Mammalian Cell | Mouse | His |
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| RTCD1-7836M | Recombinant Mouse RTCD1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| RTCD1-7836M-B | Recombinant Mouse RTCD1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
RTCD1 involved in several pathways and played different roles in them. We selected most pathways RTCD1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RTCD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
RTCD1 has several biochemical functions, for example, ATP binding,RNA binding,RNA-3-phosphate cyclase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RTCD1 itself. We selected most functions RTCD1 had, and list some proteins which have the same functions with RTCD1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| nucleotide binding | PTK2AB,SMC2,RAB1,LARP6,CSNK1G2B,ATP8B1,MAP2K4B,C10orf28,PTK6B,P2RX4A |
| poly(A) RNA binding | NOL7,C1orf35,HIST2H4A,WIBG,RPS26,RPL23A,ANXA11,RPS5,NUDT16L1,SRP19 |
| catalytic activity | PCYT1BA,DPYDB,PDXDC1,HOGA1,PHKB,CKMT1,DIP2BA,ACSL1,ISOC2B,UQCRC2B |
| ATP binding | UBE2D1A,SUCLG1,ABCD3B,ENTPD8,ADCY8,UBE2L3A,MAPK12B,FER,HELZ2,PPP1CA |
| RNA-3-phosphate cyclase activity | RTCA |
| RNA binding | ZNF385C,TRIM71,SNRPF,SURF6,FAM120A,KHDRBS3,RPL11,TRDMT1,RBMY1B,GRB7 |
| ligase activity | PDZRN3,CBX4,UBE2KA,UBE2F,ZSWIM2,UBE2L3B,GATB,TRIM9,HERC6,KCMF1 |
Interacting Protein
RTCD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RTCD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RTCD1.
Resources
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References
- Tanaka, N; Smith, P; et al. Structure of the RNA 3 '-Phosphate Cyclase-Adenylate Intermediate Illuminates Nucleotide Specificity and Covalent Nucleotidyl Transfer. STRUCTURE 18:449-457(2010).
- Moreno-Gonzalez, G; Zarain-Herzberg, A; et al. Role of glutamate receptors during neuronal differentiation. SALUD MENTAL 29:38-48(2006).
