RPS24
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Official Full Name
ribosomal protein S24 -
Overview
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S24E family of ribosomal proteins. It is located in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Mutations in this gene result in Diamond-Blackfan anemia. -
Synonyms
RPS24;ribosomal protein S24;40S ribosomal protein S24;S24;DBA3;DKFZp686N1586
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- Chicken
- Rat
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- Myc&DDK
- GST
Involved Pathway
RPS24 involved in several pathways and played different roles in them. We selected most pathways RPS24 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPS24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome | MRPS11,MRPL10,MRPL9,RPS15,MRPL23,RPLP1,RPL23,RPS4X,MRPL19,RPL37A |
Protein Function
RPS24 has several biochemical functions, for example, nucleotide binding,poly(A) RNA binding,structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by RPS24 itself. We selected most functions RPS24 had, and list some proteins which have the same functions with RPS24. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| translation initiation factor binding | EIF3C,EIF3M,EIF2B5,ZFP259,LIN28A,ZNF259,EIF2B3,EIF3F,POLR2G,EIF3BA |
| structural constituent of ribosome | RPS12,MRPS15,RPS8A,RPL13A,SLC25A24L,RPL11,MRPS36,MRPS22,SLC25A15A,RPS27.2 |
| poly(A) RNA binding | TFRC,ENO1,RPP25,FKBP3,ALDH18A1,SLC16A3,P4HB,DDX18,CCDC47,MRPS9 |
| nucleotide binding | ZNF143B,DNM2B,ACTR2A,PSPC1,ATP2B1B,RAB18B,RBM18,HNRNPA0L,VDAC3,SETD1BA |
Interacting Protein
RPS24 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPS24 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPS24.
VCAM1;ACTB;PCBD1;NFKB2;TFCP2;TAF9;MAP3K14;STK17B;PAH;PNISR;midostaurin;ere_dna
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References
- LI, ML; CENTER, MS; et al. REGULATION OF RIBOSOMAL-PROTEIN S25 IN HL-60 CELLS ISOLATED FOR RESISTANCE TO ADRIAMYCIN. FEBS LETTERS 298:142-144(1992).
- Badhai, J; Frojmark, AS; et al. Posttranscriptional down-regulation of small ribosomal subunit proteins correlates with reduction of 18S rRNA in RPS19 deficiency. FEBS LETTERS 583:2049-2053(2009).
