RPP25
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Official Full Name
ribonuclease P/MRP 25kDa subunit -
Synonyms
RPP25;ribonuclease P/MRP 25kDa subunit;30361;ENSG00000178718;15q24.2;FLJ20374;ribonuclease P protein subunit p25;ribonuclease P protein subunit p25;RNase P protein subunit p25;ribonuclease P 25kDa subunit;EC 3.1.26.5
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cells
- HEK293
- His
- His&Fc&Avi
- Myc&DDK
- N-His&C-Myc
- Flag
Involved Pathway
RPP25 involved in several pathways and played different roles in them. We selected most pathways RPP25 participated on our site, such as Ribosome biogenesis in eukaryotes,RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPP25 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA transport | EIF2S2,FXR2,NXF2,THOC5,SNUPN,SUMO1,PABPC4,EIF5,BAT1,SEH1L |
| Ribosome biogenesis in eukaryotes | UTP18,NOL6,GNL2,RPP30,NOB1,TCOF1,RRP7A,RAN,IMP3,MPHOSPH10 |
Protein Function
RPP25 has several biochemical functions, for example, poly(A) RNA binding,protein binding,ribonuclease P activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RPP25 itself. We selected most functions RPP25 had, and list some proteins which have the same functions with RPP25. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | LARP4,RPL10,HNRNPL,HNRNPDL,MYO18A,DDX10,XRN2,ELAVL2,STRAP,PRPF40A |
| protein binding | PRL,TMPRSS2,ASB7,ALS2CR11,EDF1,PDZD11,RARRES3,PEX1,POLR2L,RAB5C |
| ribonuclease P activity | POP4,RPP38,RPP30,POP1,POP5,RPP14,POP7,RPP40 |
Interacting Protein
RPP25 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPP25 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPP25.
TERF2IP;POP7;RPP14;POP4;POP5;POP1
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References
- Mahler, M; Fritzler, MJ; et al. Autoantibodies to the mitochondrial RNA processing (MRP) complex also known as Th/To autoantigen. AUTOIMMUNITY REVIEWS 14:254-257(2015).
- Mahler, M; Satoh, M; et al. Autoantibodies to the Rpp25 Component of the Th/To Complex are the Most Common Antibodies in Patients with Systemic Sclerosis without Antibodies Detectable by Widely Available Commercial Tests. JOURNAL OF RHEUMATOLOGY 41:1334-1343(2014).
