RPL6
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Official Full Name
ribosomal protein L6 -
Overview
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L6E family of ribosomal proteins. It is located in the cytoplasm. The protein can bind specifically to domain C of the tax-responsive enhancer element of human T-cell leukemia virus type 1, and it has been suggested that the protein may participate in tax-mediated transactivation of transcription. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. -
Synonyms
RPL6;ribosomal protein L6;TXREB1;60S ribosomal protein L6;L6;TAXREB107;Neoplasm-related protein C140;TAX-responsive enhancer element-binding protein 107;OTTHUMP00000241860;OTTHUMP00000241861;OTTHUMP00000241862;DNA-binding protein TAXREB107;SHUJUN-2
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rhesus macaque
- Rat
- Chicken
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- His&Fc&Avi
Involved Pathway
RPL6 involved in several pathways and played different roles in them. We selected most pathways RPL6 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPL6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome | RPL4,RPL22L1,RPL18,RPL3L,MRPL22,RPLP2L,MRPL3,RPL21,MRPS9,RPL38 |
Protein Function
RPL6 has several biochemical functions, for example, DNA binding,RNA binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPL6 itself. We selected most functions RPL6 had, and list some proteins which have the same functions with RPL6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural constituent of ribosome | MRPS31,RPL36AL,UBA52,MRPS2,MRPL14,RPS16,MRPL4,RPL27,RPLP2,RPL23A |
| RNA binding | ADARB2,SNRPA,CPEB1B,SRSF1A,SARNP,RPL27A,CWC15,CPSF1,C14orf166,EIF4G2A |
| DNA binding | ZFP287,ANG,HIST1H4G,LHX8,FOXO6,TFDP3,ZNF311,ZBTB43,HIST1H2AF,ZNF711 |
| poly(A) RNA binding | MYO18A,TPT1,WDR46,TAF15,TNRC6B,SF3B2,ZFR,DZIP3,EIF3H,SSB |
Interacting Protein
RPL6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPL6 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPL6.
STAU1;ESR1;CSNK2A1;YWHAZ;NFKB2;MAP3K14;MT-ND1;ITGB3BP;NPAS2;SEL1L;IVNS1ABP;Tpx2;Max;midostaurin;Trip11;ssrna_ug
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