RPL28
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Official Full Name
ribosomal protein L28 -
Overview
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L28E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. -
Synonyms
RPL28;ribosomal protein L28;60S ribosomal protein L28;FLJ43307;L28;FLJ 43307;L 28;RPL 28
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rhesus macaque
- E.coli
- Mammalian Cell
- HEK293
- GST
- His
- His&GST
- Non
- His&Fc&Avi
Involved Pathway
RPL28 involved in several pathways and played different roles in them. We selected most pathways RPL28 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPL28 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome | RPS19,RPLP0,MRPL13,RPS27,RPL5B,RPS3A,RPL34-PS1,RPL36,RPL5,RPL41 |
Protein Function
RPL28 has several biochemical functions, for example, RNA binding,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPL28 itself. We selected most functions RPL28 had, and list some proteins which have the same functions with RPL28. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | LARP4,GNL3,RBM19,SRSF5,PRKDC,TXN,PRRC2A,MRPL28,PRDX1,DDX24 |
| RNA binding | SETD1B,DIMT1,Aff2,TTC6,TIMM50,OASL1,HNRNPA2B1,PPARGC1B,MPHOSPH6,NPM1 |
| structural constituent of ribosome | RPL39L,MRPS23,RPL18,RPS12,RPL39,RPS27.2,MRPS9,RPL24,RPL17,MRPS11 |
| protein binding | PPP2R2C,CDC20,RNF111,TTC8,KIAA0368,GAGE1,OLR1,C12orf5,UPK3A,TFDP2 |
Interacting Protein
RPL28 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPL28 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPL28.
CCNDBP1;DCC;4505953;RTCA;MAGEB2;PSTPIP1;LYAR;UBE2D1;UBE2D3;MAP2K5;SMAD4;TMEM230;Srp72;Smad6;GABARAP
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