RPL27A
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Official Full Name
ribosomal protein L27a -
Overview
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed pseudogenes derived from this gene are dispersed through the genome. -
Synonyms
RPL27A;ribosomal protein L27a;60S ribosomal protein L27a;L27A;FLJ43464
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rhesus macaque
- Chicken
- Rat
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- His&Fc&Avi
Involved Pathway
RPL27A involved in several pathways and played different roles in them. We selected most pathways RPL27A participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPL27A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome | MRPL22,MRPS18C,RPS20,RPLP2L,MRPL12,RPL37,MRPL14,RPS3,RPS4X,RPL10 |
Protein Function
RPL27A has several biochemical functions, for example, RNA binding,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPL27A itself. We selected most functions RPL27A had, and list some proteins which have the same functions with RPL27A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | PRPF4B,MRPS9,CCT4,FLNA,RBMS2,YTHDF1,NDUFV3,LYAR,GANAB,CCDC59 |
| protein binding | IFITM1,TP73,MTA2,CWC15,UBR1,VPS37A,SMG5,TMEM74,DYRK2,TBC1D10C |
| RNA binding | ZBP1,CNOT4B,DOM3Z,SRP14,RBM15B,NR0B1,Akap17b,NPM1,BOLL,HNRNPU |
| structural constituent of ribosome | RPS23,RPL36,RPS21,RPL3,RPS27A,RPS2,RPS29,MRPS7,MRPL41,RPS4Y1 |
Interacting Protein
RPL27A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPL27A here. Most of them are supplied by our site. Hope this information will be useful for your research of RPL27A.
VCAM1;GTF2F2;ESR1;MDM2;MAP3K14;PRKACB;PEX6;midostaurin;ssrna_ug
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References
- Zsogon, A; Szakonyi, D; et al. Ribosomal Protein RPL27a Promotes Female Gametophyte Development in a Dose-Dependent Manner. PLANT PHYSIOLOGY 165:1133-1143(2014).
- Sukegawa, S; Miyake, T; et al. Multiple marker effects of single nucleotide polymorphisms in three genes, AKIRIN2, EDG1 and RPL27A, for marbling development in Japanese Black cattle. ANIMAL SCIENCE JOURNAL 85:193-197(2014).
