RPA4
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Official Full Name
replication protein A4, 30kDa -
Overview
This gene encodes a single-stranded DNA-binding protein that is the 30-kDa subunit of the replication protein A complex. Replication protein A is an essential factor for DNA double-strand break repair and cell cycle checkpoint activation. The encoded protein localizes to DNA repair foci and may be involved in the cellular DNA damage response. This protein may also play a role in inhibiting viral replication. -
Synonyms
RPA4;replication protein A4, 30kDa;replication protein A4, 34kDa;replication protein A 30 kDa subunit;HSU24186;RP-A p30;RF-A protein 4;replication factor A protein 4;replication protein A complex 34 kd subunit homolog Rpa4;MGC120333;MGC120334
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RPA4-2367H | Recombinant Human RPA4, His-tagged | E.coli | Human | His | 1-261aa | |
| RPA4-2240HCL | Recombinant Human RPA4 293 Cell Lysate | HEK293 | Human | Non |
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| RPA4-267H | Recombinant Human RPA4 protein, GST-tagged | E.coli | Human | GST | 1-261 aa |
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| RPA4-5299H | Recombinant Human RPA4 protein, His-tagged | E.coli | Human | His | 1-260aa |
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| RPA4-626H | Recombinant Human RPA4 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
RPA4 involved in several pathways and played different roles in them. We selected most pathways RPA4 participated on our site, such as DNA replication,Nucleotide excision repair,Mismatch repair, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Nucleotide Excision Repair | CHD1L,RAD23B,COPS4,ERCC5,RFC4,ZFP830,GTF2H2C,COPS2,GTF2H2C_2,COPS5 |
| Mismatch repair | RPA1,MSH3,LIG1,POLD4,PCNA,POLD1,RPA3,RFC3,RFC5,RFC4 |
| Fanconi Anemia Pathway | RPA2,RMI1,FANCC,SLX4,PMS2,SLX1B,ERCC1,DCLRE1A,FANCD2,BLM |
| DNA Replication | GINS3,PCNA,POLE3,RFC5,MCM4,RFC1,MCM2,FEN1,RNASEH2A,MCM6 |
| Homologous recombination | EME1,SSBP1,BRCA2,XRCC2,RAD51D,RAD51,SYCP3,NBN,CDK5R2,TOP3B |
Protein Function
RPA4 has several biochemical functions, for example, single-stranded DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPA4 itself. We selected most functions RPA4 had, and list some proteins which have the same functions with RPA4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| single-stranded DNA binding | PURA,RAD51D,XPC,DMC1,TDP2,HNRNPK,PMS1,RPA3,SSBP1,RBMS1 |
Interacting Protein
RPA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPA4.
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