RORB

  • Official Full Name

    RAR-related orphan receptor B

  • Overview

    The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation.

  • Synonyms

    RORB;RAR-related orphan receptor B;nuclear receptor ROR-beta;NR1F2;ROR BETA;RZRB;bA133M9.1;Nuclear receptor RZR beta;Nuclear receptor RZR-beta;Nuclear receptor subfamily 1 group F member 2;OTTHUMP00000021486;RAR related orphan receptor B;RAR related orphan receptor beta;Retinoic acid binding receptor beta;Retinoid-related orphan receptor-beta;RORB_HUMAN;RZR BETA;RAR-related orphan receptor beta;retinoic acid-binding receptor beta;retinoid-related orphan receptor beta;nuclear receptor subfamily 1 group F me;ROR-BETA;RZR-BETA

Recombinant Proteins

  • Human
  • Mouse
  • Rhesus macaque
  • Zebrafish
  • Chicken
  • E.coli
  • Mammalian Cells
  • HEK293
  • Wheat Germ
  • In Vitro Cell Free System
  • GST
  • His
  • DDK
  • Myc
  • Non
  • Flag
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
RORB-2359H Recombinant Human RORB, GST-tagged E.coli Human GST 106-459aa
RORB-14380M Recombinant Mouse RORB Protein Mammalian Cells Mouse His
RORB-2360H Recombinant Human RORB protein, MYC/DDK-tagged HEK293 Human DDK&Myc
RORB-30957TH Recombinant Human RORB Wheat Germ Human Non 459 amino acids
RORB-3956R Recombinant Rhesus monkey RORB Protein, His-tagged Mammalian Cells Rhesus macaque His
RORB-5248Z Recombinant Zebrafish RORB Mammalian Cells Zebrafish His
RORB-6650C Recombinant Chicken RORB Mammalian Cells Chicken His
RORB-2246HCL Recombinant Human RORB 293 Cell Lysate HEK293 Human Non
RORB-2163HFL Recombinant Full Length Human RORB protein, Flag-tagged Mammalian Cells Human Flag Full L.
RORB-3773R Recombinant Rhesus Macaque RORB Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
RORB-3773R-B Recombinant Rhesus Macaque RORB Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
RORB-438HF Recombinant Full Length Human RORB Protein In Vitro Cell Free System Human Full L. 459 amino acids
Rorb-5575M Recombinant Mouse Rorb Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
RORB-6489H Recombinant Human RORB Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
RORB-7707M Recombinant Mouse RORB Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
RORB-7707M-B Recombinant Mouse RORB Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    RORB involved in several pathways and played different roles in them. We selected most pathways RORB participated on our site, such as Circadian rhythm, which may be useful for your reference. Also, other proteins which involved in the same pathway with RORB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Circadian rhythm FBXW11,CRY2,PRKAB1,PRKAG1,RBX1,PRKAA1,RORC,BHLHE40,CUL1,PER1

    Protein Function

    RORB has several biochemical functions, for example, RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding,protein binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RORB itself. We selected most functions RORB had, and list some proteins which have the same functions with RORB. You can find most of the proteins on our site.

    Function Related Protein
    protein binding PVRL1,RPS2,RPH3A,C9orf142,TPP1,FGF13,SCN5A,RPUSD4,C5,TMEM59
    zinc ion binding MMP30,MTA2,RNF17,NR3C2,RNF19B,ZDHHC23B,NR2F1,RNF38,IRGF4,RNF212
    transcription factor activity, sequence-specific DNA binding PPARDB,PPARA,ATF7A,CDX1A,ZNF789,HNF1A,REL,FEV,CLOCK,GPBP1L1
    sequence-specific DNA binding CSRNP2,POU2F1A,EN2,PRRXL1,HOXA4,TEFB,LMX1BA,HOXC5,CENPB,ZGPAT
    steroid hormone receptor activity RXRBB,RARGB,NR1D2A,RORC,NR2C1,PPARG,ESR2A,VDRA,RARB,NR5A1A
    RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding PPARG,NR2F2,PPARAA,NR0B1,NR2F6B,ESRRB,PGR,RORAA,NR1H2,PPARA

    Interacting Protein

    RORB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RORB here. Most of them are supplied by our site. Hope this information will be useful for your research of RORB.

    Clock;BHLHE40;RORC;CSNK2B

    Resources

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