RLBP1
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Official Full Name
retinaldehyde binding protein 1 -
Overview
The protein encoded by this gene is a 36-kD water-soluble protein which carries 11-cis-retinaldehyde or 11-cis-retinal as physiologic ligands. It may be a functional component of the visual cycle. Mutations of this gene have been associated with severe rod-cone dystrophy, Bothnia dystrophy (nonsyndromic autosomal recessive retinitis pigmentosa) and retinitis punctata albescens. [provided by RefSeq, Jul 2008] -
Synonyms
RLBP1;retinaldehyde binding protein 1;CRALBP;retinaldehyde-binding protein 1;cellular retinaldehyde-binding protein;cellular retinaldehyde-binding protein-1
Recombinant Proteins
- Human
- Chicken
- Mouse
- E.coli
- HEK293
- Mammalian Cells
- Wheat Germ
- In Vitro Cell Free System
- His
- Myc&DDK
- Non
- Flag
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RLBP1-2315H | Recombinant Human RLBP1, His-tagged | E.coli | Human | His | 1-317aa | |
| RLBP1-18H | Recombinant Human RLBP1, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| RLBP1-2194C | Recombinant Chicken RLBP1 | Mammalian Cells | Chicken | His |
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| RLBP1-26519TH | Recombinant Human RLBP1 | Wheat Germ | Human | Non | 317 amino acids |
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| RLBP1-425H | Recombinant Human retinaldehyde binding protein 1, His-tagged | E.coli | Human | His | 1-317 a.a. |
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| RLBP1-5026H | Recombinant Human RLBP1, His-tagged | E.coli | Human | His |
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| RLBP1-2328HCL | Recombinant Human RLBP1 293 Cell Lysate | HEK293 | Human | Non |
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| RLBP1-3129H | Recombinant Human RLBP1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| RLBP1-436HF | Recombinant Full Length Human RLBP1 Protein | In Vitro Cell Free System | Human | Full L. 317 amino acids |
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| Rlbp1-5528M | Recombinant Mouse Rlbp1 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| RLBP1-6612HFL | Recombinant Full Length Human RLBP1, Flag-tagged | Mammalian Cells | Human | Flag | Full L. |
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Involved Pathway
RLBP1 involved in several pathways and played different roles in them. We selected most pathways RLBP1 participated on our site, such as Disease,Diseases associated with visual transduction,Diseases of signal transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with RLBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Visual phototransduction | NMT1B,DHRS3,DHRS9,LRP12,MYO7AA,RDH12,SDR9C7,METAP2A,GUCA1E,RLBP1A |
| The retinoid cycle in cones (daylight vision) | OPN1LW1,RLBP1A,RBP3,DHRS3,OPN1LW2,OPN1SW1,RLBP1B,DHRS3A,IRBP |
| The canonical retinoid cycle in rods (twilight vision) | MYO7A,RLBP1A,RPE65B,RPE65A,RBP4,RLBP1B,RDH10,RBP3,RDH12,ABCA4A |
| Signal Transduction | RDH14B,BCL9,PYGO2,MKL1,SOUL3,RPGRIP1L,RDH7,ARHGAP4A,SEPT7,FST |
| Diseases of signal transduction | MIB1,HDAC5,RBP1,OPN1MW2,KREMEN1,MYO18A,CPSF6,CTBP1,CDK8,TRAT1 |
| Retinoid cycle disease events | RBP1,STRA6,RBP4 |
| Disease | FGFR1OP2,GYG1,KREMEN2,CCDC167,KERA,HDAC5,RDBP,CUX1,TCEB3,IPO5 |
| Diseases associated with visual transduction | RBP1,OPN1MW2,OPN1SW,RBP4,OPN1LW,OPN1MW,STRA6,TTR |
Protein Function
RLBP1 has several biochemical functions, for example, 11-cis retinal binding,retinol binding,transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RLBP1 itself. We selected most functions RLBP1 had, and list some proteins which have the same functions with RLBP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 11-cis retinal binding | OPN5,OPN4 |
| retinol binding | ADH4,RBP2,CRABP1,ADH7,RBP7,RBP5,RBP1,RBP4,CRABP2,RBP3 |
| transporter activity | CLVS1,CRABP2,ATP5G1,SCARB1,SLCO1F1,CLVS2,CRABP1A,PDZK1,ABCC1,TTPA |
Interacting Protein
RLBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RLBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RLBP1.
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References
- Powner, MB; Gillies, MC; et al. Perifoveal Muller Cell Depletion in a Case of Macular Telangiectasia Type 2. OPHTHALMOLOGY 117:2407-2416(2010).
