RELT
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Official Full Name
RELT tumor necrosis factor receptor -
Overview
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. -
Synonyms
RELT;RELT tumor necrosis factor receptor;TNFRSF19L, tumor necrosis factor receptor superfamily, member 19 like;tumor necrosis factor receptor superfamily member 19L;FLJ14993;Receptor expressed in lymphoid tissues;OTTHUMP00000237525;OTTHUMP00000237533;TNFRSF19L
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- Cynomolgus
- HEK293
- Insect Cell
- E.coli
- Mammalian Cell
- Human Cell
- Human Cells
- Mammalian cells
- His
- C-His&hFc
- His&Fc
- Non
- Fc
- hIgG4
- His&Fc&Avi
Involved Pathway
RELT involved in several pathways and played different roles in them. We selected most pathways RELT participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with RELT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | CCL15,PDGFB,Il23a; Il12b,CSF2,CCL2,CCL23,TNF,BMP7,BMPR1B,NGFRB |
Protein Function
RELT has several biochemical functions, for example, tumor necrosis factor-activated receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RELT itself. We selected most functions RELT had, and list some proteins which have the same functions with RELT. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| tumor necrosis factor-activated receptor activity | TNFRSF1B,TNFRSF9,TNFRSF8,TNFRSF11B,TNFRSF6B,TNFRSF10A,TNFRSF4,Tnfrsf26,TNFRSF10B,NRADD |
Interacting Protein
RELT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RELT here. Most of them are supplied by our site. Hope this information will be useful for your research of RELT.
RELT Related Signal Pathway
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References
