RDM1
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Official Full Name
RAD52 motif 1 -
Overview
This gene encodes a protein involved in the cellular response to cisplatin, a drug commonly used in chemotherapy. The protein encoded by this gene contains two motifs: a motif found in RAD52, a protein that functions in DNA double-strand breaks and homologous recombination, and an RNA recognition motif (RRM) that is not found in RAD52. The RAD52 motif region in RAD52 is important for protein function and may be involved in DNA binding or oligomerization. Alternatively spliced transcript variants encoding different isoforms have been reported. -
Synonyms
RDM1;RAD52 motif 1;RAD52 homolog B (S. cerevisiae) , RAD52B;RAD52 motif-containing protein 1;MGC33977;RAD52 homolog B;RAD52B
Recombinant Proteins
- Mouse
- Rhesus macaque
- Chicken
- Cynomolgus
- Human
- Mammalian Cells
- HEK293
- His
- Non
- His&Fc&Avi
Involved Pathway
RDM1 involved in several pathways and played different roles in them. We selected most pathways RDM1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RDM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
RDM1 has several biochemical functions, for example, DNA binding,RNA binding,nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RDM1 itself. We selected most functions RDM1 had, and list some proteins which have the same functions with RDM1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | TAL2,ZNF329,TBX5A,HIST2H2AC,RAD51AP1,ZFP521,CHD4,PIAS1,STAT5B,VPS72 |
| nucleotide binding | MOV10B.1,STK24A,CELF6,CPEB1B,TLK1A,GIMAP3,MYO1EB,SFRS3B,RBM18,MAPK14B |
| RNA binding | RPL24,EIF4E1C,EIF2C3,CTU1,KHDC1A,SRSF1B,RBMS1,RAE1,KHDC1,PRAC |
| protein binding | ECM1,IGF2R,EMP2,NR0B2,RECK,CBLB,BMPR2,LETM1,ASS1,BCL6 |
Interacting Protein
RDM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RDM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RDM1.
MRFAP1L1
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References
- Qu, M; Yang, B; et al. Phosphorylation-Dependent Interactions between Crb2 and Chk1 Are Essential for DNA Damage Checkpoint. PLOS GENETICS 8:-(2012).
- Galamb, O; Sipos, F; et al. mRNA expression, functional profiling and multivariate classification of colon biopsy specimen by cDNA overall glass microarray. WORLD JOURNAL OF GASTROENTEROLOGY 12:6998-7006(2006).
