RDH14
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Official Full Name
retinol dehydrogenase 14 (all-trans/9-cis/11-cis) -
Overview
RDH14 exhibits an oxidoreductive catalytic activity towards retinoids. It is most efficient as an NADPH-dependent retinal reductase and displays high activity toward 9-cis and all-trans-retinol. No steroid dehydrogenase activity is detected. -
Synonyms
RDH14;retinol dehydrogenase 14 (all-trans/9-cis/11-cis);retinol dehydrogenase 14 (all trans and 9 cis);retinol dehydrogenase 14;PAN2;SDR7C4;short chain dehydrogenase/reductase family 7C;member 4;RGD1565196;3110030G19Rik;Alcohol dehydrogenase PAN2;AW215439;Pancreas protein 2;RDH14_HUMAN;Retinol dehydrogenase 14 (all trans/9 cis/11 cis);Short chain dehydrogenase/reductase family 7C member 4;UNQ529/PRO1072;retinol dehydrogenase 14 (all-trans and 9-cis);short chain dehydrogenase/reductase family 7C, member 4
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RDH14-2239H | Recombinant Human RDH14, His-tagged | E.coli | Human | His | 1-335aa | |
| RDH14-14049M | Recombinant Mouse RDH14 Protein | Mammalian Cell | Mouse | His |
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| RDH14-2436HCL | Recombinant Human RDH14 293 Cell Lysate | HEK293 | Human | Non |
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| Rdh14-274M | Recombinant Mouse Rdh14 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| RDH14-6316H | Recombinant Human RDH14 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| RDH14-7510M | Recombinant Mouse RDH14 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| RDH14-7510M-B | Recombinant Mouse RDH14 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
RDH14 involved in several pathways and played different roles in them. We selected most pathways RDH14 participated on our site, such as RA biosynthesis pathway,Signal Transduction,Signaling by Retinoic Acid, which may be useful for your reference. Also, other proteins which involved in the same pathway with RDH14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signal Transduction | ARHGEF1B,KREMEN2,ARHGAP36,KIF14,CDON,RLN1,APOC2,MDKA,WWOX,GMIP |
| Signaling by Retinoic Acid | CRABP2,CRABP1,RDH7,DHRS3,RDH10,PDK3B,ALDH8A1,CRABP2B,CRABP2A,RDH14A |
| RA biosynthesis pathway | SDR16C5,ADH8A,RDH10,CYP26A1,DHRS3,DHRS4,CRABP1A,CRABP1B,DHRS9,RDH14B |
Protein Function
RDH14 has several biochemical functions, for example, alcohol dehydrogenase (NADP+) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RDH14 itself. We selected most functions RDH14 had, and list some proteins which have the same functions with RDH14. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| alcohol dehydrogenase (NADP+) activity | AKR1A1B,AKR1A1A,ALDH3A1 |
Interacting Protein
RDH14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RDH14 here. Most of them are supplied by our site. Hope this information will be useful for your research of RDH14.
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