RBM14
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Official Full Name
RNA binding motif protein 14 -
Overview
This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene. -
Synonyms
RBM14;RNA binding motif protein 14;RNA-binding protein 14;COAA;coactivator activator;DKFZp779J0927;SIP;SYT interacting protein;SYTIP1;paraspeckle protein 2;SYT-interacting protein;transmembrane protein 137;synaptotagmin-interacting protein;RR
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RBM14-13990M | Recombinant Mouse RBM14 Protein | Mammalian Cells | Mouse | His |
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| RBM14-31045TH | Recombinant Human RBM14, His-tagged | E.coli | Human | His | Full L. 1-669 a.a. |
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| RBM14-4722H | Recombinant Human RBM14 protein, His-SUMO-tagged | E.coli | Human | His&SUMO | 1-669aa |
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| RBM14-7469M | Recombinant Mouse RBM14 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| RBM14-7469M-B | Recombinant Mouse RBM14 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
RBM14 involved in several pathways and played different roles in them. We selected most pathways RBM14 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RBM14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
RBM14 has several biochemical functions, for example, RNA binding,RNA polymerase II transcription cofactor activity,ligand-dependent nuclear receptor transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RBM14 itself. We selected most functions RBM14 had, and list some proteins which have the same functions with RBM14. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | LSM3,KHDRBS1,OASL1,TPD52L2,MKRN2,TSR1,NXF1,HIST1H4B,YWHAZ,MKI67 |
| RNA binding | HNRPKL,METTL3,ZFR,IMPDH1,BOLL,IFIT8,KIAA0907,PCBP2,DPPA5A,ZNF385C |
| protein binding | GAS2L3,UBE2D2,FNBP1,SHC1,FBL,ITGAL,GMCL1,KATNBL1,C19orf46,MAPK10 |
| ligand-dependent nuclear receptor transcription coactivator activity | ENY2,ATXN7L3,AASS,MED4,NCOA2,PPARGC1A,CALCOCO1,WDR77,HELZ2,MED14 |
| nucleotide binding | WRNIP1,UCK2A,MAPK14A,GNA13A,MXA,PANK1A,MAP3K4,CHD1L,KIF4,SETX |
| RNA polymerase II transcription cofactor activity | MED13A,MED7,MED24,NKX2,MED10,FOXH1,MED13,MED14,CNOT2,TP53BP1 |
| protein binding, bridging | BCL3,NMD3,SH2D1B,NEFL,FLRT3,STX1A,CAV1,ST13,FRMD4A,BFAR |
Interacting Protein
RBM14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RBM14 here. Most of them are supplied by our site. Hope this information will be useful for your research of RBM14.
ESR1;ESR2;QKI;pre-let-7a
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References
- Bhuvanakantham, R; Ng, ML; et al. West Nile virus and dengue virus capsid protein negates the antiviral activity of human Sec3 protein through the proteasome pathway. CELLULAR MICROBIOLOGY 15:1688-1706(2013).
- Zan, H; Casali, P; et al. Regulation of Aicda expression and AID activity. AUTOIMMUNITY 46:83-101(2013).
