RASGRF1

  • Official Full Name

    Ras protein-specific guanine nucleotide-releasing factor 1

  • Overview

    The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

  • Synonyms

    RASGRF1;Ras protein-specific guanine nucleotide-releasing factor 1;GRF1;ras-specific guanine nucleotide-releasing factor 1;CDC25;CDC25L;GNRP;GRF55;H GRF55;PP13187;guanine nucleotide exchange factor;guanine nucleotide-releasing protein;guanine

Recombinant Proteins

  • Rat
  • Human
  • Mouse
  • Mammalian Cell
  • Mammalian cells
  • HEK293
  • HEK293T
  • His
  • Flag
  • His&Fc&Avi
  • Myc&DDK

    Involved Pathway

    RASGRF1 involved in several pathways and played different roles in them. We selected most pathways RASGRF1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RASGRF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    RASGRF1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by RASGRF1 itself. We selected most functions RASGRF1 had, and list some proteins which have the same functions with RASGRF1. You can find most of the proteins on our site.

    Function Related Protein

    Interacting Protein

    RASGRF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RASGRF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RASGRF1.

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