RAP2B
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Official Full Name
RAP2B, member of RAS oncogene family -
Overview
This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated. -
Synonyms
RAP2B;RAP2B, member of RAS oncogene family;ras-related protein Rap-2b;Ras family small GTP binding protein RAP2B;Ras related protein RAP 2B;small GTP binding protein;MGC20484
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Chicken
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Avi
- Fc
- DDK
- Myc
Involved Pathway
RAP2B involved in several pathways and played different roles in them. We selected most pathways RAP2B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RAP2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
RAP2B has several biochemical functions, for example, GDP binding,GTP binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RAP2B itself. We selected most functions RAP2B had, and list some proteins which have the same functions with RAP2B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PTGES3,CALD1,CD8B1,SAV1,CRYBB1,PEX1,EXOSC5,IRS4,KNG1,TWF2 |
| protein domain specific binding | NDE1,TACC1,RHOA,ATP1A1,GABRR1,HOMER3,COX4I2,PLG,ZNF521,HAND2 |
| GTP binding | ARL8B,DNAJC27,GNAI2A,MFHAS1,RHEB,RAP1AB,GIMAP8,ADSSL,EIF2S3Y,NMUR2 |
| GDP binding | RAB9B,PCK1,SRP54,RAB17,EIF2B1,RAB22A,RAB7L1,RAB7,PRPS2,RAB28 |
Interacting Protein
RAP2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAP2B here. Most of them are supplied by our site. Hope this information will be useful for your research of RAP2B.
RUNDC3A;CAMK2B;RASSF5;VCAM1;pi3p;FN1;MME
Resources
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References
- Paganini, S; Guldetti, GF; et al. Identification and biochemical characterization of Rap2C, a new member of the Rap family of small GTP-binding proteins. BIOCHIMIE 88:285-295(2006).
- Lin, S; Sahai, A; et al. High glucose stimulates synthesis of fibronectin via a novel protein kinase C, Rap1b, and B-Raf signaling pathway. JOURNAL OF BIOLOGICAL CHEMISTRY 277:41725-41735(2002).
