RAD54B
-
Official Full Name
RAD54 homolog B -
Overview
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. -
Synonyms
RAD54B;RAD54 homolog B (S. cerevisiae);DNA repair and recombination protein RAD54B;RDH54
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RAD54B-13876M | Recombinant Mouse RAD54B Protein | Mammalian Cell | Mouse | His |
|
|
| RAD54B-6275C | Recombinant Chicken RAD54B | Mammalian Cell | Chicken | His |
|
|
| RAD54B-1460HCL | Recombinant Human RAD54B cell lysate | Human | Non |
|
||
| RAD54B-7391M | Recombinant Mouse RAD54B Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| RAD54B-7391M-B | Recombinant Mouse RAD54B Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
RAD54B involved in several pathways and played different roles in them. We selected most pathways RAD54B participated on our site, such as Homologous recombination, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAD54B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Homologous recombination | RPA3,RAD51B,MRE11A,CDK5R2,MUS81,BRCA2,POLD2,POLD4,RAD54L,RAD52 |
Protein Function
RAD54B has several biochemical functions, for example, ATP binding,DNA binding,DNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RAD54B itself. We selected most functions RAD54B had, and list some proteins which have the same functions with RAD54B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | HSPD1,MYLK,AK4,CHD8,ACVR1BA,STK24A,CDK7,SMARCA4A,GRK7A,NLRP11 |
| RNA helicase activity | DDX6,PRIM2,DHX16,CHST13,DDX10,SKIV2L2,DDX24,CCDC111,UAP1L1,DDX5 |
| DNA helicase activity | DNA2,MCM2,SUPV3L1,CHD8,WRN,PIF1,IGHMBP2,RUVBL2,MCM6L,RECQL5 |
| DNA binding | MSXB,ZFP541,MCM2,RBPJA,ZKSCAN5,PARP4,HOXD12,PBX1,DRGX,HIST1H2BJ |
| DNA translocase activity | ATRX,FBXO18 |
Interacting Protein
RAD54B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAD54B here. Most of them are supplied by our site. Hope this information will be useful for your research of RAD54B.
q8n374_human;TRAPPC6A;IGFBP3;PSMA1;CSNK1E;UBE2I;BAAT;CCDC33;LNX1;DYRK2;SFRP2;C9orf156;RIBC2;GORASP2;CDC23;ZNF580
Resources
Related Services
Related Products
References
