RABIF
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Official Full Name
RAB interacting factor -
Overview
This gene encodes a member of the SCE4/YPT1/RAB family of small GTP-binding proteins that are involved in the regulation of intracellular vesicular transport. This protein stimulates GTP-GDP exchange in SEC4, and to a lesser extent in YPT1 and RAB3A, and may play a general role in vesicular transport. -
Synonyms
RABIF;RAB interacting factor;RASGRF3;guanine nucleotide exchange factor MSS4;mss4;Mammalian suppressor of SEC4;Ras specific guanine releasing factor 3;RASGFR3;rab-interacting factor;Ras-specific guanine-releasing factor 3
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Avi
- Fc
- DDK
- Myc
Involved Pathway
RABIF involved in several pathways and played different roles in them. We selected most pathways RABIF participated on our site, such as RB in Cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with RABIF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RB in Cancer | HMGB2,HLTF,RBP1,SMARCA2,PRMT2,FAF1,TOP2A,ANLN,DCK |
Protein Function
RABIF has several biochemical functions, for example, guanyl-nucleotide exchange factor activity,protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RABIF itself. We selected most functions RABIF had, and list some proteins which have the same functions with RABIF. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | ADAMTS4,Car9,ZDHHC15,RC3H1,TRIM35-1,LMO3,BMI1B,RNF150A,PHF15,TRAF7 |
| guanyl-nucleotide exchange factor activity | ARFGEF2,RALGPS1,RASGEF1BB,GDPGP1,DOCK4,DOCK7,ARHGEF3L,ANKRD27,TRIOA,ARHGEF4 |
| protein binding | NAALADL2,CTSZ,VEPH1,C8orf48,CECR2,FBLIM1,HOMER3,ITSN1,PPIL2,LXN |
Interacting Protein
RABIF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RABIF here. Most of them are supplied by our site. Hope this information will be useful for your research of RABIF.
TCF4;RAB3A;REL;RASSF5;RAB8A;TERF2IP;LAMTOR5;hmuS;ZNF544;CCBL2
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References
- Uno, T; Isoyama, Y; et al. Characterization of Rab-interacting lysosomal protein in the brain of Bombyx mori. HISTOCHEMISTRY AND CELL BIOLOGY 141:311-320(2014).
- Richardson, SCW; Winistorfer, SC; et al. Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton. MOLECULAR BIOLOGY OF THE CELL 15:1197-1210(2004).
