Rabggta
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Official Full Name
Rab geranylgeranyltransferase, alpha subunit -
Overview
subunit of Rab geranylgeranyl transferase, which catalyses the transfer of geranylgeranyl groups to Rab protein cysteine residues. -
Synonyms
RABGGTA;Rab geranylgeranyltransferase, alpha subunit;geranylgeranyl transferase type-2 subunit alpha;protein prenyltransferase alpha subunit repeat containing 3;PTAR3;Geranylgeranyl transferase type 2 subunit alpha;Geranylgeranyl transferase type II subunit alpha;PGTA_HUMAN;Rab geranyl geranyltransferase subunit alpha;Rab geranyl-geranyltransferase subunit alpha;Rab geranylgeranyltransferase alpha subunit;Rab geranylgeranyltransferase subunit alpha;Rab GG transferase alpha;Rab GGTase alpha
Recombinant Proteins
- Mouse
- Human
- Rat
- Zebrafish
- Mammalian Cell
- Wheat Germ
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
Rabggta involved in several pathways and played different roles in them. We selected most pathways Rabggta participated on our site, such as Signaling events mediated by PRL, which may be useful for your reference. Also, other proteins which involved in the same pathway with Rabggta were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signaling events mediated by PRL | PTP4A1,PTP4A3,ATF5,LRP8,RABGGTB,PTP4A2 |
Protein Function
Rabggta has several biochemical functions, for example, Rab GTPase binding,Rab geranylgeranyltransferase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Rabggta itself. We selected most functions Rabggta had, and list some proteins which have the same functions with Rabggta. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| Rab geranylgeranyltransferase activity | RABGGTB,FNTA |
| zinc ion binding | ZFP330,LNX2,MBD1,MT1E,CAD,ZCCHC9,MGRN1,ADH6,AQPEP,CIZ1 |
| Rab GTPase binding | RHOBTB3,NSF,TMEM127,CCDC64,RAB11FIP3,GDI1,Fert2,RILP,SYTL3,MYO5B |
Interacting Protein
Rabggta has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Rabggta here. Most of them are supplied by our site. Hope this information will be useful for your research of Rabggta.
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References
- Charng, WL; Yamamoto, S; et al. Drosophila Tempura, a Novel Protein Prenyltransferase alpha Subunit, Regulates Notch Signaling Via Rab1 and Rab11. PLOS BIOLOGY 12:-(2014).
- Lachance, V; Cartier, A; et al. Regulation of beta(2)-Adrenergic Receptor Maturation and Anterograde Trafficking by an Interaction with Rab Geranylgeranyltransferase MODULATION OF Rab GERANYLGERANYLATION BY THE RECEPTOR. JOURNAL OF BIOLOGICAL CHEMISTRY 286:40802-40813(2011).
