RAB6A
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Official Full Name
RAB6A, member RAS oncogene family -
Overview
Rab6 is a member of the Ras superfamily of small Rab GTPases implicated in endocytosis. The three distinct members of the Rab6 subfamily (Rab6A, Rab6A, and Rab6B) are structurally similar but likely exhibit non-overlapping functions. Rab6 localized to the -
Synonyms
RAB6A;RAB6A, member RAS oncogene family;RAB6;ras-related protein Rab-6A;Rab GTPase;RAB6, member RAS oncogene family
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Chicken
- Rhesus macaque
- E.coli
- Mammalian Cells
- HEK293
- GST
- Non
- His
- Strep
- DDK
- Myc
- SUMO
- Avi
- Fc
Involved Pathway
RAB6A involved in several pathways and played different roles in them. We selected most pathways RAB6A participated on our site, such as Pre-NOTCH Expression and Processing,Pre-NOTCH Processing in Golgi,Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAB6A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pre-NOTCH Expression and Processing | TMED2 |
| Signaling by NOTCH | DTX2,DNER,TLE3,MDKB,MDKA,HEYL,TLE4,MDK,TLE2,DLK1 |
| Signal Transduction | MOB1BA,AMOTL2,ANXA1A,ABCA4A,LPAR2A,NMT1A,WIF1,IFT88,MYO7A,PTHRP2 |
Protein Function
RAB6A has several biochemical functions, for example, GTP binding,GTPase activity,myosin V binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RAB6A itself. We selected most functions RAB6A had, and list some proteins which have the same functions with RAB6A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| myosin V binding | RAB25,RAB3D,RAB8A,RAB3B,RAB39B,RAB14,RAB27B,RAB6B,RAB10,RAB11B |
| GTP binding | RAB24,NKIRAS2,RRAGD,GNAT1,RABL2A,RAP1B,IFT22,ARL15,RERGLA,RAB10 |
| protein domain specific binding | VPS4A,KPNB1,YWHAE,WNT5A,NDE1,CALM,PTPN11,PLXND1,DICER1,ARHGEF4 |
| protein binding | MYLK,RRAD,RORA,ACVR2A,DERL1,HNRNPUL1,NITR9,CCDC87,MED31,CLUAP1 |
| GTPase activity | MFN1,GNAO1B,MTG1,GNA15.1,MTIF2,GNL3L,ARHGDIB,RAB37,GEM,RRAD |
Interacting Protein
RAB6A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAB6A here. Most of them are supplied by our site. Hope this information will be useful for your research of RAB6A.
OCRL;PMM1;GCC2;1-phosphatidyl-1d-myo-inositol 3,4,5-trisphosphate
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