RAB2A
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Official Full Name
RAB2A, member RAS oncogene family -
Overview
The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
RAB2A;RAB2A, member RAS oncogene family;RAB2, RAB2, member RAS oncogene family;ras-related protein Rab-2A;OTTMUSP00000004796;9330148M11Rik;C80220;GTP binding protein;RAB2;RAB2 member RAS oncogene family;RAB2A_HUMAN;Ras related protein Rab 2A;RAS-associated protein RAB2;RP23-183L6.1;small GTP binding protein RAB2A;RAB2, member RAS oncogene family;LHX
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- Rat
- Chicken
- Cynomolgus
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Avi
- Fc
- Flag
- DDK
- Myc
- SUMO
Involved Pathway
RAB2A involved in several pathways and played different roles in them. We selected most pathways RAB2A participated on our site, such as AMPK signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAB2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| AMPK signaling pathway | RAB10,PPP2R1B,ELAVL1,CREB1,GYS2,PCK1,PIK3R1,PPP2CA,ULK1,PPP2CB |
Protein Function
RAB2A has several biochemical functions, for example, GDP binding,GTP binding,GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RAB2A itself. We selected most functions RAB2A had, and list some proteins which have the same functions with RAB2A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GDP binding | RAB8B,RAB3B,RAB8A,IIGP1,RAB11B,RAB28,RAB22A,RAP1B,RAB5B,RAB7L1 |
| protein binding | MED18,OLIG3,CPS1,REL,NAA11,NFKBIB,CXXC11,PRKAR1A,P2RY6,BMP1A |
| GTP binding | RAB7B,DIRAS1,GLUD2,TUBA1C,GNA11A,GNAO1,EEF2B,HSP90AB1,RAC1B,GNL1 |
| GTPase activity | DIRAS3,RAB11BA,GNAI3,GNA12,IIGP1,DNM1L,RAB32A,GSPT2,EFTUD2,ARL4D |
Interacting Protein
RAB2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAB2A here. Most of them are supplied by our site. Hope this information will be useful for your research of RAB2A.
GOLGA2;FAM71C;STAMBPL1;ICA1;FAM114A1;BLZF1
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