RAB1A
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Official Full Name
RAB1A, member RAS oncogene family -
Overview
This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms. -
Synonyms
RAB1A;RAB1A, member RAS oncogene family;RAB1;ras-related protein Rab-1A;Rab GTPase YPT1 homolog (yeast);YPT1;DKFZP564B163;GTP binding protein RAB 1A;GTP Binding Protein RAB1A;RAB 1;Rab 1A;RAB1, member RAS oncogene family;RAB1A member RAS oncogene family;RAB1A_HUMAN;Ras related protein Rab 1A;Ras-associated protein RAB1;YPT1 related protein;YPT1-related protein;Rab GTPase YPT1 homolog
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- Chicken
- E.coli
- Mammalian Cells
- HEK293
- GST
- His&GST
- His
- Non
- Myc&DDK
- Flag
- His&Fc&Avi
Involved Pathway
RAB1A involved in several pathways and played different roles in them. We selected most pathways RAB1A participated on our site, such as Legionellosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAB1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Legionellosis | Itgam&Itgb2,IL12A,IL18,Casp3,IL6,ITGAM,CASP7,NFKBIA,NFKB1,VCP |
Protein Function
RAB1A has several biochemical functions, for example, GTP binding,GTPase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RAB1A itself. We selected most functions RAB1A had, and list some proteins which have the same functions with RAB1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activity | ARL8A,GTPBP1,RAB18B,GSPT1L,RAB8A,RHOF,RALAB,GEM,RAP1B,RAB39A |
| protein binding | CDH23,NEUROG3,MARK2,ARL11,OGG1,UXT,PIH1D2,SLC22A17,KIFAP3,PROP1 |
| GTP binding | RAB40B,DIRAS1,ERAS,ERAL1,TUBAL3,URGCP,LGALS6,TUBB4A,GUCY1B3,EEF1A1 |
Interacting Protein
RAB1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAB1A here. Most of them are supplied by our site. Hope this information will be useful for your research of RAB1A.
drrA;gtp;OCRL
Resources
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References
- Tanaka, M; Mun, S; et al. Hsc70 Contributes to Cancer Cell Survival by Preventing Rab1A Degradation under Stress Conditions. PLOS ONE 9:-(2014).
- Zenner, HL; Yoshimura, S; et al. Analysis of Rab GTPase-Activating Proteins Indicates that Rab1a/b and Rab43 Are Important for Herpes Simplex Virus 1 Secondary Envelopment. JOURNAL OF VIROLOGY 85:8012-8021(2011).
