QTRT1

  • Official Full Name

    queuine tRNA-ribosyltransferase 1
  • Overview

    This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a;heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine;queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of;this gene is located on the long arm of chromosome X.
  • Synonyms

    QTRT1;queuine tRNA-ribosyltransferase 1;queuine tRNA-ribosyltransferase;TGT;tRNA guanine transglycosylase;Guanine insertion enzyme;Queuine tRNA ribosyltransferase;TGUT;tRNA-guanine transglycosylase;FP3235

Recombinant Proteins

  • Zebrafish
  • Mouse
  • Rat
  • Human
  • Mammalian Cells
  • E.coli
  • HEK293
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
QTRT1-11243Z Recombinant Zebrafish QTRT1 Mammalian Cells Zebrafish His
QTRT1-13773M Recombinant Mouse QTRT1 Protein Mammalian Cells Mouse His
QTRT1-4869R Recombinant Rat QTRT1 Protein Mammalian Cells Rat His
QTRT1-79H Recombinant Human QTRT1, His-tagged E.coli Human His
QTRT1-2634HCL Recombinant Human QTRT1 293 Cell Lysate HEK293 Human Non
QTRT1-4528R Recombinant Rat QTRT1 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
QTRT1-4528R-B Recombinant Rat QTRT1 Protein Pre-coupled Magnetic Beads HEK293 Rat
QTRT1-7330M Recombinant Mouse QTRT1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
QTRT1-7330M-B Recombinant Mouse QTRT1 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    QTRT1 involved in several pathways and played different roles in them. We selected most pathways QTRT1 participated on our site, such as Gene Expression,tRNA modification in the nucleus and cytosol,tRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with QTRT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    tRNA processing FAM98B,POP1,RPP14,TPRKB,C14orf166,TYW1,RPP40,TP53RK,ADAT2,THG1L
    tRNA modification in the nucleus and cytosol TRMT112,TYW5,THG1L,TYW1,TRMT1,TRMT11,LAGE3,PUS7,KIAA1456,MANEA
    Gene Expression DDOST,TAF1B,BRF2,SLC38A8,CHD4,ZNF543,TXN,ZNF287,SUZ12A,ZNF43

    Protein Function

    QTRT1 has several biochemical functions, for example, metal ion binding,contributes_to queuine tRNA-ribosyltransferase activity,queuine tRNA-ribosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by QTRT1 itself. We selected most functions QTRT1 had, and list some proteins which have the same functions with QTRT1. You can find most of the proteins on our site.

    Function Related Protein
    metal ion binding ACMSD,DEM1,ZBTB3,SP5A,THAP7,ZNF157,CYGB1,ITGAV,ZDHHC16,PRMT3
    contributes_to queuine tRNA-ribosyltransferase activity MANEA,QTRTD1

    Interacting Protein

    QTRT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with QTRT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of QTRT1.

    ARF6;PA;ZBTB16;UNC119;SETDB1;COPS6;SH3GL3;NDUFA4L2

    Resources

    References

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